Berrill Jane, James Peter, Michanikou Antonis, Galanakis Emmanouil, Michaelidou Eleni, Kinni Paraskevi, Kalivitis Nikos, Kouvarakis Giorgos, Vasiliadou Emily, Savvides Chrysanthos, Tymvios Filippos, Koutrakis Petros, Yiallouros Panayiotis K, Kouis Panayiotis
Department of Environmental Health, Harvard TH Chan School of Public Health, Harvard University, Boston, USA.
Medical School, University of Cyprus, Nicosia, Cyprus.
Sci Rep. 2025 Jan 22;15(1):2886. doi: 10.1038/s41598-025-87426-5.
Personal characteristics, unfavorable weather conditions and air pollution have been linked with reduced physical activity in children. However, among children with asthma the effects of these parameters remain unclear. This study objectively quantified the physical activity of children with asthma and evaluated its association with environmental, personal, and clinical parameters. Participants of the prospective LIFE-MEDEA asthma study wore the EMRACE™ smartwatch daily for continuous monitoring of physical activity and acquisition of global positioning system data. Daily physical activity, personal and clinical data were combined with daily temperature, precipitation, and air pollution levels in adjusted mixed effect regression models to examine the relationship between physical activity and the examined parameters. For a follow-up period of 4 months, 186 children with asthma demonstrated a decrease of 796 steps (95% CI: -1080, -512) on days with precipitation compared to non-precipitation days and a decrease of 96 steps (95% CI: -182, -9) for every 10 µg/m increase in PM. The relationship between temperature and daily steps was characterized by an inverted U-shape. There was also evidence that gender and age-adjusted BMI z-score were negatively associated with daily steps. These results can further inform the design of physical activity interventions targeting children with asthma.
个人特征、不利的天气条件和空气污染与儿童身体活动减少有关。然而，在哮喘儿童中，这些因素的影响仍不明确。本研究客观地量化了哮喘儿童的身体活动，并评估了其与环境、个人和临床参数的关联。前瞻性LIFE-MEDEA哮喘研究的参与者每天佩戴EMRACE™智能手表，以持续监测身体活动并获取全球定位系统数据。在调整后的混合效应回归模型中，将每日身体活动、个人和临床数据与每日温度、降水量和空气污染水平相结合，以检验身体活动与所研究参数之间的关系。在4个月的随访期内，186名哮喘儿童在有降水的日子比无降水的日子步数减少了796步（95%CI：-1080，-512），并且每增加10µg/m的PM，步数减少96步（95%CI：-182，-9）。温度与每日步数之间的关系呈倒U形。也有证据表明，经性别和年龄调整的BMI z评分与每日步数呈负相关。这些结果可为针对哮喘儿童的身体活动干预措施的设计提供进一步参考。
