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Investigation of sensory attenuation in the somatosensory domain using EEG in a novel virtual reality paradigm.

作者信息

Giannini Gianluigi, Nierhaus Till, Blankenburg Felix

机构信息

Neurocomputation and Neuroimaging Unit (NNU), Freie Universität Berlin, Berlin, Germany.

Berlin School of Mind and Brain, Humboldt Universität zu Berlin, Berlin, Germany.

出版信息

Sci Rep. 2025 Jan 22;15(1):2819. doi: 10.1038/s41598-025-87244-9.


DOI:10.1038/s41598-025-87244-9
PMID:39843944
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11754869/
Abstract

We are not only passively immersed in a sensorial world, but we are active agents that directly produce stimulations. Understanding what is unique about sensory consequences can give valuable insight into the action-perception-cycle. Sensory attenuation is the phenomenon that self-produced stimulations are perceived as less intense compared to externally-generated ones. Studying this phenomenon, however, requires considering a plethora of factors that could otherwise interfere with its interpretation, such as differences in stimulus properties, attentional resources, or temporal predictability. We therefore developed a novel Virtual Reality (VR) setup which allows control over several of these confounding factors. Furthermore, we modulated the expectation of receiving a somatosensory stimulation across self-production and passive perception through a simple probabilistic learning task, allowing us to test to what extent the electrophysiological correlates of sensory attenuation are impacted by stimulus expectation. Therefore, the aim of the present study was twofold: first we aimed validating a novel VR paradigm during electroencephalography (EEG) recoding to investigate sensory attenuation in a highly controlled setup; second, we tested whether electrophysiological differences between self- and externally-generated sensations could be better explained by stimulus predictability factors, corroborating the validity of sensory attenuation. Results of 26 participants indicate that early (P100), mid-latency (P200) and later negative contralateral potentials were significantly attenuated by self-generated sensations, independent of the stimulus expectation. Moreover, a component around 200 ms post-stimulus at frontal sites was found to be enhanced for self-produced stimuli. The P300 was influenced by stimulus expectation, regardless of whether the stimulation was actively produced or passively attended. Together, our results demonstrate that VR opens up new possibilities to study sensory attenuation in more ecological valid yet well-controlled paradigms, and that sensory attenuation is not significantly modulated by stimulus predictability, suggesting that sensory attenuation relies on motor-specific predictions about their sensory outcomes. This not only supports the phenomenon of sensory attenuation, but is also consistent with previous research and the concept that action actually plays a crucial role in perception.

摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2580/11754869/6390773222fc/41598_2025_87244_Fig4_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2580/11754869/85674f4dd635/41598_2025_87244_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2580/11754869/67d7167da2f9/41598_2025_87244_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2580/11754869/3db7553efb74/41598_2025_87244_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2580/11754869/6390773222fc/41598_2025_87244_Fig4_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2580/11754869/85674f4dd635/41598_2025_87244_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2580/11754869/67d7167da2f9/41598_2025_87244_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2580/11754869/3db7553efb74/41598_2025_87244_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2580/11754869/6390773222fc/41598_2025_87244_Fig4_HTML.jpg

相似文献

[1]
Investigation of sensory attenuation in the somatosensory domain using EEG in a novel virtual reality paradigm.

Sci Rep. 2025-1-22

[2]
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[3]
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[4]
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[5]
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[6]
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[7]
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[8]
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[9]
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[10]
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本文引用的文献

[1]
Comparing auditory distance perception in real and virtual environments and the role of the loudness cue: A study based on event-related potentials.

Hear Res. 2024-3-15

[2]
Sensory Attenuation Deficit and Auditory Hallucinations in Schizophrenia: A Causal Mechanism or a Risk Factor? Evidence From Meta-Analyses on the N1 Event-Related Potential Component.

Biol Psychiatry. 2024-8-1

[3]
Using event-related brain potentials to evaluate motor-auditory latencies in virtual reality.

Front Neuroergon. 2023-7-5

[4]
Neural Applications Using Immersive Virtual Reality: A Review on EEG Studies.

IEEE Trans Neural Syst Rehabil Eng. 2023

[5]
Perception of self-generated and externally-generated visual stimuli: Evidence from EEG and behavior.

Psychophysiology. 2023-8

[6]
Virtual occlusion effects on the perception of self-initiated visual stimuli.

Conscious Cogn. 2023-1

[7]
Active tactile discrimination is coupled with and modulated by the cardiac cycle.

Elife. 2022-10-12

[8]
Tactile motor attention induces sensory attenuation for sounds.

Conscious Cogn. 2022-9

[9]
Electrophysiological correlates of in vivo and virtual reality exposure therapy in spider phobia.

Psychophysiology. 2022-12

[10]
Temporal uncertainty enhances suppression of neural responses to predictable visual stimuli.

Neuroimage. 2021-10-1

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