Nielsen J, Aagaard J, Toftgaard C
Acta Chir Scand. 1985;151(1):49-55.
A series of 779 patients with gastric cancer diagnosed in the 20-year period 1960-1979 is presented. Surgery was performed in 86% of the cases, but was judged to be radical in only 28%. The operative mortality in the total period was 14.3%, with a fall in the final 5-year period. Patient age, stage of cancer and radicality of operation were prognostic factors as regards survival time. The overall 5-year survival rate was 12%. The rate was 37% after radical surgery, increasing to 49% when corrected for age and sex. The survival rate was unchanged during the period of the study. The crude 5-year survival among the patients with radical surgery was 41% and was independent of the type of surgery. Median age was significantly lower in the patients with early-stage cancer than in the series as a whole. The numbers of younger patients increased during the last ten years of the study.
本文呈现了1960年至1979年这20年间确诊的779例胃癌患者的情况。86%的病例接受了手术,但只有28%的手术被判定为根治性手术。整个时期的手术死亡率为14.3%,在最后一个5年期间有所下降。患者年龄、癌症分期和手术根治性是影响生存时间的预后因素。总体5年生存率为12%。根治性手术后的生存率为37%,校正年龄和性别后升至49%。研究期间生存率无变化。根治性手术患者的粗5年生存率为41%,且与手术类型无关。早期癌症患者的中位年龄显著低于整个系列患者。在研究的最后十年中,年轻患者的数量有所增加。