Ogawa Soichiro, Yaginuma Kei, Harigane Yuki, Makabe Shunta, Imai Hitomi, Meguro Satoru, Tanji Ryo, Onagi Akifumi, Honda-Takinami Ruriko, Matsuoka Kanako, Hoshi Seiji, Hata Junya, Sato Yuichi, Akaihata Hidenori, Kataoka Masao, Uemura Motohide, Kojima Yoshiyuki
Department of Urology, Fukushima Medical University School of Medicine, 1, Hikarigaoka, Fukushima, 960-1295, Japan.
BMC Urol. 2025 Jan 23;25(1):14. doi: 10.1186/s12894-025-01696-9.
Long-term survival can be achieved in patients with localized prostate cancer (PCa). Therefore, maintenance of postoperative quality of life (QOL) and treatment satisfaction are important. Although longitudinal changes in disease-specific QOL are reported, there are few studies investigating which factors longitudinally affect treatment satisfaction in patients who undergo robot-assisted radical prostatectomy (RARP). Therefore, we examined the factors associated with treatment satisfaction over the first 12 months postoperatively based on an assessment using a patient-reported questionnaire.
Of the 612 consecutive patients who underwent RARP, 408 patients were enrolled in this study and divided into a satisfied group and a non-satisfied group at every evaluation timepoint. Multivariate logistic regression analysis was conducted to clarify factors affecting the postoperative treatment satisfaction between the two groups.
Multivariate logistic regression analysis revealed that factors relating to treatment satisfaction had longitudinally changed. Urinary bother (UB) (odds ratio (OR) = 1.023; p = 0.008), and sexual function (SF) (OR = 0.941; p = 0.004) were the significant factors associated with treatment satisfaction at 1 month postoperatively; UB (OR = 1.040; p = 0.001) and sexual bother (SB) (OR = 1.019; p < 0.001) at 3 months; urinary function (UF) (OR = 1.027; p = 0.008), UB (OR = 1.035; p = 0.011), SB (OR = 1.013; p = 0.009), and hormonal bother (HB) (OR = 1.065; p = 0.023) at 6 months; UF (OR = 1.026; p = 0.008), UB (OR = 1.030; p = 0.029), and SB (OR = 1.014; p = 0.004) at 9 months; UF (OR = 1.024; p = 0.002) at 12 months.
Treatment satisfaction in patients who underwent RARP changed over time. Our results suggest that giving sufficient information before treatment choice is both important and useful for patients' decision-making, leading to improved patient QOL.
局限性前列腺癌(PCa)患者可实现长期生存。因此,维持术后生活质量(QOL)和治疗满意度很重要。尽管有关于疾病特异性QOL纵向变化的报道,但很少有研究调查哪些因素会纵向影响接受机器人辅助根治性前列腺切除术(RARP)患者的治疗满意度。因此,我们基于患者报告问卷评估,研究了术后前12个月与治疗满意度相关的因素。
在612例连续接受RARP的患者中,408例患者纳入本研究,并在每个评估时间点分为满意组和不满意组。进行多因素逻辑回归分析以阐明两组之间影响术后治疗满意度的因素。
多因素逻辑回归分析显示,与治疗满意度相关的因素随时间发生了变化。术后1个月,排尿困扰(UB)(比值比(OR)=1.023;p=0.008)和性功能(SF)(OR=0.941;p=0.004)是与治疗满意度相关的显著因素;术后3个月,UB(OR=1.040;p=0.001)和性困扰(SB)(OR=1.019;p<0.001);术后6个月,排尿功能(UF)(OR=1.027;p=0.008)、UB(OR=1.035;p=0.011)、SB(OR=1.013;p=0.009)和激素困扰(HB)(OR=1.065;p=0.023);术后9个月,UF(OR=1.026;p=0.008)、UB(OR=1.030;p=0.029)和SB(OR=1.014;p=0.004);术后12个月,UF(OR=1.024;p=0.002)。
接受RARP患者的治疗满意度随时间而变化。我们的结果表明,在治疗选择前提供充分信息对患者决策既重要又有用,可改善患者的QOL。