Dunn Isaac B J M D, Power Emma, Casey Liam J, Wootton Bethany M
Discipline of Clinical Psychology, Graduate School of Health, University of Technology, Sydney, New South Wales, Australia.
Department of Speech Pathology, Graduate School of Health, University of Technology, Sydney, New South Wales, Australia.
PLoS One. 2025 Jan 24;20(1):e0316857. doi: 10.1371/journal.pone.0316857. eCollection 2025.
Cognitive behavior therapy (CBT) is a well-established treatment for anxiety disorders in the general population. However, the efficacy of CBT for lesbian, gay, bisexual, transgender, queer, questioning, and otherwise non-heterosexual or non-cisgender (LGBTQ+) people with anxiety disorders is still emerging in the literature. This protocol proposes an exploratory, two-group, randomized controlled trial comparing the efficacy of CBT for anxiety disorders against a waitlist control group.
The trial will recruit 52 LGBTQ+ adults with a primary anxiety disorder diagnosis. The treatment will consist of videoconferencing-delivered CBT using the Unified Protocol (UP). The treatment will be provided in eight weekly individual sessions. Following treatment completion, the waitlist control participants will receive an LGBTQ+ adapted CBT intervention delivered via videoconferencing. The control group will receive the LGBTQ+ adapted UP in weekly sessions for eight weeks. Diagnostic status and symptom severity will be assessed at baseline, post-treatment, and three-month follow-up. Post-treatment qualitative exit interviews will collect participant perspectives on treatment acceptability.
Outcome measures will be compared across groups and benchmarked with existing literature to assess efficacy and feasibility, while qualitative analysis will explore intervention acceptability.
The results are anticipated to inform best-practice remote transdiagnostic treatment of anxiety disorders in LGBTQ+ people.
认知行为疗法(CBT)是普通人群焦虑症的一种成熟治疗方法。然而,CBT对患有焦虑症的女同性恋、男同性恋、双性恋、跨性别者、酷儿、疑问者以及其他非异性恋或非顺性别者(LGBTQ+)的疗效在文献中仍在不断涌现。本方案提出一项探索性的两组随机对照试验,比较CBT对焦虑症的疗效与候补对照组。
该试验将招募52名被诊断患有原发性焦虑症的LGBTQ+成年人。治疗将采用统一方案(UP)通过视频会议提供CBT。治疗将在八次每周一次的个体治疗中进行。治疗完成后,候补对照组参与者将通过视频会议接受适合LGBTQ+的CBT干预。对照组将在八周内每周接受适合LGBTQ+的UP治疗。将在基线、治疗后和三个月随访时评估诊断状态和症状严重程度。治疗后的定性退出访谈将收集参与者对治疗可接受性的看法。
将对各组的结果指标进行比较,并与现有文献进行对比,以评估疗效和可行性,而定性分析将探索干预的可接受性。
预期结果将为LGBTQ+人群焦虑症的最佳远程跨诊断治疗提供参考。