[Liver regeneration at different stages of mononuclear infiltration induced by zymosan granules].

The relationship between regeneration of the liver of (CBA X C57BL)F1 mice and the degree of its mononuclear infiltration was studied. Resection of the 2/3 of the liver mass was performed 1 and 5 days and 2 months after zymosan-induced mononuclear infiltration. The synthesis of DNA and mitotic activity of hepatocytes in the liver with infiltrations was higher as compared with control. The rate of liver regeneration was dependent on the scope of the mononuclear infiltration, reaching a maximum provided liver resection was made 5 days after injection of zymosan granules.