Javidi Sobhan, Sadrizadeh Sepehr, Sadrizadeh Ali, Bonakdaran Shokoufeh, Jarahi Lida
Department of Medicine, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
Cardiothoracic Surgery and Transplant Research Center, Imam Reza Hospital, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
Sci Rep. 2025 Jan 29;15(1):3705. doi: 10.1038/s41598-024-79860-8.
The choice between total thyroidectomy (TT) and subtotal thyroidectomy (STT) can affect postoperative complications and long-term outcomes in these patients. This study aimed to investigate postoperative complications and long-term outcomes in patients who underwent TT and STT. This retrospective study investigated 1.022 patients who admitted to Ghaem and Razavi hospitals, Mashhad, and underwent thyroidectomy between 2011 and 2017. Data related to postoperative complications, recurrence rate and overall survival were collected and analyzed. The data collection tool used in this research was a checklist. In this study, women accounted for 863 and men for 159 of the total population. The highest number of thyroidectomy surgeries was found in 2013 and in all years the majority of thyroidectomy surgeries were performed on women. The results demonstrated that 71.2% of the patients underwent TT and 28.8% underwent STT. The percentage rate of recurrent laryngeal nerve injury after thyroidectomy surgery (regardless of the type of selected surgery) was 6.1%, affecting 62 individuals. No significant relationship was observed between the type of selected surgery and damage to this nerve (P > 0.05). In addition, a statistically significant correlation was reported between thyroidectomy and suffering from hypocalcemia (P < 0.05). The study revealed that TT was associated with a higher postoperative complication rate compared to STT. Individual treatment plans must be developed based on the risks and benefits of each surgical approach.
甲状腺全切除术（TT）和甲状腺次全切除术（STT）之间的选择会影响这些患者的术后并发症和长期预后。本研究旨在调查接受TT和STT的患者的术后并发症和长期预后。这项回顾性研究调查了1022名入住马什哈德的加姆医院和拉扎维医院并于2011年至2017年间接受甲状腺切除术的患者。收集并分析了与术后并发症、复发率和总生存率相关的数据。本研究使用的数据收集工具是一份清单。在本研究中，女性占总人口的863人，男性占159人。甲状腺切除术手术数量最多的年份是2013年，并且在所有年份中，大多数甲状腺切除术手术都是针对女性进行的。结果表明，71.2%的患者接受了TT，28.8%的患者接受了STT。甲状腺切除术后喉返神经损伤的发生率（无论所选手术类型如何）为6.1%，有62人受影响。所选手术类型与该神经损伤之间未观察到显著相关性（P>0.05）。此外，据报道甲状腺切除术与低钙血症之间存在统计学上的显著相关性（P<0.05）。研究表明，与STT相比，TT的术后并发症发生率更高。必须根据每种手术方法的风险和益处制定个体化的治疗方案。
