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口干的管理

Management of Dry Mouth.

作者信息

Hayslett Renee L, Marshall Leisa L

机构信息

Mercer University College of Pharmacy, Atlanta, Georgia.

出版信息

Sr Care Pharm. 2025 Feb 1;40(2):55-63. doi: 10.4140/TCP.n.2025.55.

Abstract

Dry mouth, or xerostomia, is a common complaint among older people. Dry mouth can result in a variety of dental complications, oral discomfort, difficulty swallowing and eating, and decreased taste sensation, all of which can adversely affect quality of life. To provide an overview of the definition, diagnosis, causes, potential complications, and treatment strategies for dry mouth. PubMed, Proquest, Cochrane Library, drug prescribing information, drug information databases, and manufacturers' websites were used. Search terms were "xerostomia," "dry mouth," "hyposalivation," "causes," "treatment," and "pharmacology." The resources identified included clinical practice guidelines, review articles, and original research articles. The literature described the causes and treatment strategies for managing xerostomia, including concerns for older adults, and pharmacists' involvement for providing care. The most common cause of dry mouth in the general population and in older adults is medication use. Individual medications may cause dry mouth, primarily through anticholinergic side effects. Polypharmacy is also a cause. Other causes are dehydration, alcohol and caffeine intake, and systemic diseases such as Sjögren's disease. If not addressed, individuals experiencing chronic dry mouth are at increased risk for various oral conditions such as dental caries, periodontal disease, and infections. Interventions such as good oral hygiene methods, using saliva substitutes containing xylitol and prescription cholinergic agonists, if appropriate, can reduce symptoms and complications. Pharmacists can play an important role in managing dry mouth by conducting medication reviews, providing patient education for oral health practices, and recommending treatment strategies.

摘要

口干,即口腔干燥症,是老年人常见的主诉。口干会导致多种牙齿并发症、口腔不适、吞咽和进食困难以及味觉减退,所有这些都会对生活质量产生不利影响。本文旨在概述口干的定义、诊断、病因、潜在并发症及治疗策略。我们使用了PubMed、Proquest、Cochrane图书馆、药品处方信息、药物信息数据库和制造商网站。检索词为“口腔干燥症”“口干”“唾液分泌减少”“病因”“治疗”和“药理学”。所识别的资源包括临床实践指南、综述文章和原始研究文章。文献描述了管理口腔干燥症的病因和治疗策略,包括对老年人的关注以及药剂师在提供护理方面的参与。普通人群和老年人中口干最常见的原因是药物使用。个别药物可能导致口干,主要是通过抗胆碱能副作用。同时服用多种药物也是一个原因。其他原因包括脱水、酒精和咖啡因摄入以及系统性疾病,如干燥综合征。如果不加以解决,长期口干的个体患各种口腔疾病的风险会增加,如龋齿、牙周病和感染。采取良好的口腔卫生方法、使用含木糖醇的唾液替代品以及在适当情况下使用处方胆碱能激动剂等干预措施,可以减轻症状和并发症。药剂师可以通过进行用药评估、为口腔健康实践提供患者教育以及推荐治疗策略,在管理口干方面发挥重要作用。

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