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多器官移植受者中甲硝唑诱发脑病的罕见病例：临床与影像学见解

Rare case of metronidazole-induced encephalopathy in a multiple transplant recipient: Clinical and radiological insights.

作者信息

Draidi Mahmoud, Abdullah Ibtesam, Abbarh Shahem, Kolleri Jouhar, Sawaf Bisher, Alastal Yaseen

机构信息

Department of Internal Medicine Hamad Medical Corporation Doha Qatar.

Department of Internal Medicine MedStar Health Baltimore Maryland USA.

出版信息

Clin Case Rep. 2025 Jan 31;13(2):e9544. doi: 10.1002/ccr3.9544. eCollection 2025 Feb.

DOI:10.1002/ccr3.9544
PMID:39895846
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11785462/
Abstract

Metronidazole-induced encephalopathy (MIE) is a rare but reversible condition that can present with nonspecific neurological symptoms, making early recognition and diagnosis challenging. Magnetic resonance imaging (MRI) is crucial in identifying typical brain lesions associated with MIE. Prompt discontinuation of metronidazole typically results in symptom resolution and improvement in MRI findings.

摘要

甲硝唑诱发的脑病（MIE）是一种罕见但可逆转的病症，可表现为非特异性神经症状，这使得早期识别和诊断具有挑战性。磁共振成像（MRI）对于识别与MIE相关的典型脑病变至关重要。及时停用甲硝唑通常会导致症状缓解以及MRI表现改善。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4df7/11785462/8bbd41801872/CCR3-13-e9544-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4df7/11785462/3086db8a1d25/CCR3-13-e9544-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4df7/11785462/8bbd41801872/CCR3-13-e9544-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4df7/11785462/3086db8a1d25/CCR3-13-e9544-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4df7/11785462/8bbd41801872/CCR3-13-e9544-g002.jpg

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Frequency and Risk Factor Analysis for Metronidazole-Associated Neurologic Adverse Events.甲硝唑相关神经系统不良事件的频率及危险因素分析。
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[A case of irreversible metronidazole encephalopathy during liver abscess treatment].[肝脓肿治疗期间不可逆性甲硝唑脑病1例]
Nihon Shokakibyo Gakkai Zasshi. 2023;120(10):858-867. doi: 10.11405/nisshoshi.120.858.
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Correlation of magnetic resonance images with neuropathology of irreversible metronidazole-induced encephalopathy: an autopsy case report.磁共振成像与不可逆甲硝唑诱导脑病的神经病理学相关性：一例尸检病例报告。
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