Wendelstein Jascha A, Atchison David A, Gatinel Damien, Cooke David L, Langenbucher Achim
University Eye Hospital, Ludwig-Maximilians-University, Munich, Germany.
Institut für Refraktive Und Ophthalmo-Chirurgie (IROC), Zurich, Switzerland.
Ophthalmic Physiol Opt. 2025 Mar;45(2):372-382. doi: 10.1111/opo.13443. Epub 2025 Feb 3.
To investigate the influence of the corneal epithelium on corneal power, particularly in special cases such as post-refractive surgery and keratoconus.
A retrospective observational study. Measurement data were obtained from a high-resolution anterior segment analyser (CSO MS-39). Corneal curvature and power data, as well as surface height data, were organised in a cylindrical coordinate system. Calculations considered one, two and three refractive surfaces, examining the role of epithelial thickness and stromal curvature.
The effect of the epithelium on corneal power was minimal (<0.1 D) in normal corneas, but it was considerable in keratoconus and post-refractive surgery cases, with differences up to 0.9 D. The effect decreased for larger measurement zones.
Incorporating epithelial thickness and stromal curvature into corneal power calculations is a crucial next step in accurate corneal power and intraocular lens calculation in eyes with previous refractive surgery or keratoconus. This study highlights the need for advanced diagnostic and calculation methods in complex cases.
研究角膜上皮对角膜屈光力的影响,尤其是在屈光手术后和圆锥角膜等特殊情况下。
一项回顾性观察研究。测量数据来自高分辨率眼前节分析仪(CSO MS-39)。角膜曲率和屈光力数据以及表面高度数据在柱面坐标系中进行整理。计算考虑了一个、两个和三个屈光面,研究上皮厚度和基质曲率的作用。
在正常角膜中,上皮对角膜屈光力的影响极小(<0.1 D),但在圆锥角膜和屈光手术后的病例中影响显著,差异可达0.9 D。对于较大的测量区域,这种影响会减小。
在先前有屈光手术或圆锥角膜的眼睛中,将上皮厚度和基质曲率纳入角膜屈光力计算是准确计算角膜屈光力和人工晶状体的关键下一步。本研究强调了复杂病例中先进诊断和计算方法的必要性。