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Breathing New Life into Pulmonary Arterial Hypertension Treatment: Targeting Serotonin Synthesis with an Inhalation Approach.

作者信息

Lee Michael H, Kumar Rahul

机构信息

Zuckerberg San Francisco General Hospital University of California San Francisco San Francisco, California.

出版信息

Am J Respir Cell Mol Biol. 2025 Aug;73(2):168-169. doi: 10.1165/rcmb.2025-0040ED.

Abstract
摘要

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本文引用的文献

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In vivo effects of a combined 5-HT1B receptor/SERT antagonist in experimental pulmonary hypertension.
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Converging evidence in support of the serotonin hypothesis of dexfenfluramine-induced pulmonary hypertension with novel transgenic mice.
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Am J Physiol Lung Cell Mol Physiol. 2007 Oct;293(4):L1045-52. doi: 10.1152/ajplung.00082.2007. Epub 2007 Aug 3.
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Serotonin transporter inhibitors protect against hypoxic pulmonary hypertension.
Am J Respir Crit Care Med. 2003 Aug 15;168(4):487-93. doi: 10.1164/rccm.200210-1212OC. Epub 2003 May 28.

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