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[糖皮质激素诱导的肾上腺功能不全]

[Glucocorticoid-induced adrenal insufficiency].

作者信息

Imamovic Marcus, Dahlqvist Per, Ragnarsson Oskar, Einarsdottir Margret

机构信息

ST-läkare, Medicincentrum, Norrlands universitetssjukhus, Umeå.

docent, överläkare, Norrlands universitetssjukhus.

出版信息

Lakartidningen. 2025 Feb 10;122:24090.

Abstract

Glucocorticoid-induced adrenal insufficiency is an underdiagnosed condition that possibly contributes to increased mortality. Consensus regarding management of glucocorticoid-induced adrenal insufficiency in patients receiving glucocorticoid therapy has previously been lacking, but the European Society of Endocrinology and the Endocrine Society have recently published joint international guidelines on the diagnosis and treatment, summarized in this article. To further support patients and healthcare professionals, and to prevent a potentially fatal adrenal crisis, a national blue corticosteroid treatment card has been introduced. The card is intended to be provided to patients treated with prednisolone >5 mg daily (or equivalent) for >3-4 weeks.

摘要

糖皮质激素诱导的肾上腺功能不全是一种诊断不足的疾病,可能导致死亡率增加。此前,对于接受糖皮质激素治疗的患者中糖皮质激素诱导的肾上腺功能不全的管理缺乏共识,但欧洲内分泌学会和美国内分泌学会最近发布了关于诊断和治疗的联合国际指南,本文对此进行了总结。为了进一步支持患者和医护人员,并预防潜在致命的肾上腺危象,已推出全国性蓝色皮质类固醇治疗卡。该卡旨在提供给每天接受>5毫克泼尼松龙(或等效药物)治疗>3 - 4周的患者。

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