Guided bone regeneration (GBR) is a bone augmentation technique widely used in clinical practice to promote new bone growth by creating a conducive environment through bone grafts and barrier membranes. This article reports a case of a 14-year-old patient with significant bone loss, wound breakdown, and gingival recession in the anterior maxillary tooth, which was successfully treated through GBR combined with orthodontic treatment. This complex case of an area with bone defect required a multidisciplinary treatment in order to provide the best treatment for young patients.