Jin Liuyin, Wang Dongdong, Yang Dengxian, Jin Qiong, Cao Mengye, Li Yuanyuan, Yang Jiajie, Xie Guoming, Zhang Wenwu
Ningbo University Affiliated Kangning Hospital Child and Adolescent Psychiatry Center, Ningbo, Zhejiang, China.
Science and Education Department, Lishui Second People's Hospital, Lishui, China.
Front Psychiatry. 2025 Jan 31;16:1507566. doi: 10.3389/fpsyt.2025.1507566. eCollection 2025.
This study investigates the long-term impact of perceived caregiver anxiety and stress during childhood on late-life depression. Adverse childhood experiences related to caregiver mental health may significantly influence emotional well-being, and this study utilizes data from the China Health and Retirement Longitudinal Study (CHARLS) to explore these associations.
CHARLS data were analyzed for individuals who reported perceived caregiver anxiety and stress. Depression was measured using the CES-10 depression scale. Multivariate logistic regression models examined the relationship between caregiver anxiety and stress frequency and late-life depression, adjusting for confounders like socioeconomic status, health behaviors, and demographics.
Childhood exposure to caregiver anxiety and stress significantly increased the risk of depression in later life (p < 0.05), with stronger effects observed among individuals with female caregivers. The risk escalated with the frequency of caregiver anxiety episodes. After adjusting for covariates, the association for male caregivers weakened, highlighting the potential role of other mediators.
The results highlight the critical importance of parental mental health, especially maternal anxiety, in mitigating intergenerational mental health risks. Targeted interventions for caregiver mental health, particularly for female caregivers, are crucial. Longitudinal studies are needed to better establish causality and further investigate these mechanisms.
本研究调查了童年时期感知到的照顾者焦虑和压力对晚年抑郁症的长期影响。与照顾者心理健康相关的不良童年经历可能会显著影响情绪健康,本研究利用中国健康与养老追踪调查(CHARLS)的数据来探索这些关联。
对报告感知到照顾者焦虑和压力的个体的CHARLS数据进行分析。使用CES-10抑郁量表测量抑郁症。多变量逻辑回归模型检验了照顾者焦虑和压力频率与晚年抑郁症之间的关系,并对社会经济地位、健康行为和人口统计学等混杂因素进行了调整。
童年时期暴露于照顾者的焦虑和压力中会显著增加晚年患抑郁症的风险(p < 0.05),在有女性照顾者的个体中观察到的影响更强。风险随着照顾者焦虑发作的频率而增加。在调整协变量后,男性照顾者的关联减弱,突出了其他中介因素的潜在作用。
结果强调了父母心理健康,尤其是母亲的焦虑,在减轻代际心理健康风险方面的至关重要性。针对照顾者心理健康的有针对性干预措施,特别是针对女性照顾者的措施,至关重要。需要进行纵向研究以更好地确定因果关系并进一步研究这些机制。