东南亚地区用于治疗新生儿和婴儿感染的“观察”类和“储备”类抗生素使用率很高。
High Rates of "Watch" and "Reserve" Class Antibiotics Used to Treat Infections in Neonates and Infants in Southeast Asia.
作者信息
Harrison Michelle L, Dickson Benjamin F R, Villanueva-Uy Maria Esterlita T, Dwi Putri Nina, Adrizain Riyadi, Kartina Leny, Gunaratna Gayana P S, Chandrasiri Nambage Shirani, Tran Hoang T, Nguyen Huong X, Fong Siew M, Kasahara Erena S, Le Chau H M, Soekardja Distyayu, Husada Dominicus, Hong Ng Boon, Williams Phoebe C M
机构信息
From the Sydney Institute for Infectious Diseases, The University of Sydney.
School of Public Health, Faculty of Medicine and Health, The University of Sydney, Sydney, Australia.
出版信息
Pediatr Infect Dis J. 2025 Apr 1;44(4):e113-e116. doi: 10.1097/INF.0000000000004614. Epub 2025 Jan 9.
We evaluated antibiotic prescribing practices for neonates and infants hospitalized with infections in resource-constrained healthcare settings, where antimicrobial resistance is responsible for significant neonatal morbidity and mortality. A point prevalence survey of 667 admitted infants across 10 clinical sites in Southeast Asia revealed a total of 405 antibiotics were prescribed to 218 infants, with high use of World Health Organization-classified "Watch," "Reserve" and "Not Recommended" antibiotics.
我们评估了在资源有限的医疗环境中，因感染住院的新生儿和婴儿的抗生素处方情况，在这种环境中，抗菌素耐药性导致了大量新生儿发病和死亡。对东南亚10个临床地点的667名入院婴儿进行的一项现况调查显示，共对218名婴儿开出了405剂抗生素，大量使用了世界卫生组织分类为“观察类”、“储备类”和“不建议使用类”的抗生素。
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