Firatligil Fahri Burcin, Topkara Sucu Serap, Engin Üstün Yaprak
Division of Perinatology, Department of Obstetrics and Gynecology, Ankara Bilkent City Hospital, Ankara,Türkiye.
Department of Obstetrics and Gynecology, Ankara Etlik City Hospital, Ankara,Türkiye.
Ulus Travma Acil Cerrahi Derg. 2025 Feb;31(2):125-132. doi: 10.14744/tjtes.2024.86087.
This study aims to analyze the demographic, ultrasonographic, and laboratory findings as well as the outcomes of patients with ectopic pregnancy (EP) who underwent life-saving urgent surgery.
A retrospective cross-sectional study was conducted at the Tersiyer Referral Hospital between January 01, 2016 and January 01, 2020. The study included 469 cases of EP. Data for these patients were extracted from hospital records and patient files. For the analysis of life-saving urgent surgeries, only patients presenting with severe signs and symptoms during hospital admission, follow-up, or after methotrexate (MTX) therapy were included.
The mean age of the patients was 31.2 (+-5.65) years, with the youngest being 15 years old and the oldest 49 years old. A history of EP was noted in 15.1% of patients, and 29.4% were smokers. The reasons for consulting a doctor included no complaints in 37 patients (7.9%), delayed menstruation in 37 patients (7.9%), abdominal pain in 128 patients (27.3%), abdominal pain with vaginal bleeding in 108 patients (23.0%), and only vaginal bleeding in 159 patients (33.9%). In four patients (0.9%), the ectopic focus could not be identified via ultrasound, while in 255 patients (54.3%) the ectopic focus was located in the right adnexal area. The mean preoperative hemoglobin level was 12.4 (+-1.33) g/dL, with a median hemoglobin value of 12.6 (range: 7.2-14.7 ) g/dL. A comparison of demographic data, ultrasound findings, and pre- and postoperative laboratory results between patients who underwent surgery without MTX therapy and those who underwent surgery following MTX therapy revealed significant differences in terms of age, parity, maximum diameter of the ectopic focus, preoperative hemoglobin levels, preoperative white blood cell counts, presence of free fluid in the abdomen, and contraceptive methods.
EP holds a significant place among gynecological emergencies. Any delay in diagnosis can lead to life-threatening conditions, where the only viable treatment at this stage is life-saving urgent surgical intervention.
本研究旨在分析接受挽救生命的紧急手术的异位妊娠(EP)患者的人口统计学、超声检查和实验室检查结果以及治疗结果。
于2016年1月1日至2020年1月1日在特尔西耶转诊医院进行了一项回顾性横断面研究。该研究纳入了469例EP病例。这些患者的数据从医院记录和患者档案中提取。为了分析挽救生命的紧急手术,仅纳入在入院、随访期间或甲氨蝶呤(MTX)治疗后出现严重体征和症状的患者。
患者的平均年龄为31.2(±5.65)岁,最年轻的15岁,最年长的49岁。15.1%的患者有EP病史,29.4%为吸烟者。就诊原因包括37例(7.9%)无不适、37例(7.9%)月经推迟、128例(27.3%)腹痛、108例(23.0%)腹痛伴阴道出血以及159例(33.9%)仅有阴道出血。4例(0.9%)患者经超声检查无法确定异位病灶位置,255例(54.3%)患者的异位病灶位于右侧附件区。术前血红蛋白水平的平均值为12.4(±1.33)g/dL,血红蛋白中位数为12.6(范围:7.2 - 14.7)g/dL。比较未接受MTX治疗而进行手术的患者与接受MTX治疗后进行手术的患者的人口统计学数据、超声检查结果以及术前和术后实验室检查结果,发现年龄、产次、异位病灶最大直径、术前血红蛋白水平、术前白细胞计数、腹腔内有无游离液体以及避孕方法等方面存在显著差异。
EP在妇科急症中占有重要地位。诊断的任何延迟都可能导致危及生命的情况,此时唯一可行的治疗方法是挽救生命的紧急手术干预。