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心肌病的“帕多瓦分类”分为三组:肥厚型/限制型、扩张型/运动减弱型和瘢痕形成/致心律失常型。

The 'Padua classification' of cardiomyopathies into three groups: hypertrophic/restrictive, dilated/hypokinetic, and scarring/arrhythmogenic.

作者信息

Corrado Domenico, Graziano Francesca, Bauce Barbara, Bueno Marinas Maria, Calore Chiara, Celeghin Rudy, Cipriani Alberto, De Gaspari Monica, De Lazzari Manuel, Migliore Federico, Perazzolo Marra Martina, Pilichou Kalliopi, Rigato Ilaria, Rizzo Stefania, Angelini Annalisa, Zorzi Alessandro, Thiene Gaetano, Basso Cristina

机构信息

Department of Cardio-Thoraco-Vascular Sciences and Public Health, University of Padova, Padova, Italy.

Department of Sports Medicine, Semmelweis University, Budapest, Hungary.

出版信息

Eur Heart J Suppl. 2025 Feb 19;27(Suppl 1):i73-i82. doi: 10.1093/eurheartjsupp/suae108. eCollection 2025 Feb.

Abstract

The newly proposed classification of cardiomyopathies, referred to as 'the Padua Classification', is based on both pathobiological basis (genetics, molecular biology, and pathology) and clinical features (morpho-functional and structural ventricular remodelling as evidenced by cardiac magnetic resonance). Cardiomyopathies are grouped into tree main categories and characterized by a designation combining both 'anatomical' and 'functional' features: hypertrophic/restrictive, dilated/hypokinetic, and scarring/arrhythmogenic; each cardiomyopathy group includes either genetic or non-genetic aetiologic variants. This novel approach aims to enhance the diagnostic accuracy and to support 'disease-specific' therapeutic strategies, with the objective to improve patient management and outcome.

摘要

新提出的心肌病分类法,即“帕多瓦分类法”,基于病理生物学基础(遗传学、分子生物学和病理学)以及临床特征(心脏磁共振显示的形态功能和结构心室重塑)。心肌病分为三大类,其特征是结合了“解剖学”和“功能”特征的命名:肥厚型/限制型、扩张型/运动减弱型和瘢痕型/致心律失常型;每个心肌病组都包括遗传或非遗传病因变体。这种新方法旨在提高诊断准确性并支持“疾病特异性”治疗策略,以改善患者管理和预后。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3750/11836707/70b0579636d2/suae108f1.jpg

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