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评估心脏重症监护病房中心脏重症医师的临床影响:来自RESCUE注册研究的结果。

Assessing the clinical impact of cardiac intensivists in cardiac intensivecare units: results from the RESCUE registry.

作者信息

Bae Dae-Hwan, Lee Sang Yeub, Bae Jang-Whan, Yang Jeong Hoon, Ko Young-Guk, Ahn Chul-Min, Yu Cheol Woong, Chun Woo Jung, Kwon Sung Uk, Kim Hyun-Joong, Kim Bum Sung, Kim Je Sang, Lee Wang Soo, Jang Woo Jin, Jeong Jin-Ok, Park Sang-Don, Lim Seong-Hoon, Cho Sungsoo, Gwon Hyeon-Cheol

机构信息

Regional Cardiovascular Disease Center, Chungbuk National University Hospital, Cheongju, Korea.

Division of Cardiology, Department of Medicine, Sejong General Hospital, Bucheon, Korea.

出版信息

BMC Cardiovasc Disord. 2025 Feb 21;25(1):124. doi: 10.1186/s12872-025-04559-1.

Abstract

BACKGROUND

The presence of dedicated intensive care unit (ICU) physicians is associated with reduced ICU mortality. However, the information available on the role of cardiac intensivists in cardiac ICUs (CICUs) is limited. Therefore, we investigated the association of cardiac intensivist-directed care with clinical outcomes in adult patients admitted to the CICU.

METHODS

In this retrospective study, we extracted data from the SMART-RESCUE registry, a multicenter, retrospective, and prospective registry of patients presenting with cardiogenic shock. Overall, 1,247 patients with CS were enrolled, between January 2014 and December 2018, from 12 tertiary centers in Korea. The patients were categorized into two groups based on the involvement of a cardiac intensivist in their care. The primary outcome was in-hospital mortality rate.

RESULTS

The all-cause mortality rate was 33.6%. The in-hospital mortality rate was lower (25.4%) in the cardiac intensivist group than in the non-cardiac intensivist group (40.1%). Cardiac mortality rates were 20.5% and 35.4% in the cardiac intensivist and non-cardiac intensivist groups, respectively. In patients undergoing extracorporeal membrane oxygenation, the mortality rate at centers with cardiac intensivists was 38.0%, whereas that at centers without cardiac intensivists was 62.2%. The dopamine use was lower, norepinephrine use was higher, and vasoactive-inotropic score was lower in the cardiac intensivist group than in the non-cardiac intensivist group.

CONCLUSIONS

Involvement of a cardiac intensivist in CICU patient care was associated with a reduction in in-hospital mortality rate and the administration of a low dose of vasopressors and inotropes according to the cardiogenic shock guidelines.

摘要

背景

配备专门的重症监护病房(ICU)医生可降低ICU死亡率。然而,关于心脏重症医生在心脏ICU(CICU)中作用的现有信息有限。因此,我们调查了心脏重症医生指导的治疗与入住CICU的成年患者临床结局之间的关联。

方法

在这项回顾性研究中,我们从SMART-RESCUE注册中心提取数据,该注册中心是一个关于心源性休克患者的多中心、回顾性和前瞻性注册中心。2014年1月至2018年12月期间,从韩国12个三级中心共纳入1247例心源性休克患者。根据是否有心脏重症医生参与治疗,将患者分为两组。主要结局是住院死亡率。

结果

全因死亡率为33.6%。心脏重症医生组的住院死亡率(25.4%)低于非心脏重症医生组(40.1%)。心脏重症医生组和非心脏重症医生组的心脏死亡率分别为20.5%和35.4%。在接受体外膜肺氧合的患者中,有心脏重症医生的中心死亡率为38.0%,而没有心脏重症医生的中心死亡率为62.2%。心脏重症医生组的多巴胺使用量较低,去甲肾上腺素使用量较高,血管活性药物-正性肌力药物评分低于非心脏重症医生组。

结论

心脏重症医生参与CICU患者护理与住院死亡率降低以及根据心源性休克指南给予低剂量血管升压药和正性肌力药物有关。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9dfa/11843748/ea1f400764b2/12872_2025_4559_Fig1_HTML.jpg

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