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美国目前胃静脉曲张的管理方法:提供者态度与实践的调查

Current approaches for management of gastric varices in the United States: a survey of providers' attitudes and practices.

作者信息

Hashim Mahmoud A, Elfert Khaled, Afifi Ahmed M, Hassan Manal, Elkheshen Ahmed, Gagneja Harish, Patel Kalpesh, Satapathy Sanjaya, Kowdley Kris, Jalal Prasun K

机构信息

Department of Internal Medicine, SBH Health System - St. Barnabas Hospital, New York City, New York, USA.

Division of Gastroenterology and Hepatology, West Virginia University, Morgantown, West Virginia, USA.

出版信息

Proc (Bayl Univ Med Cent). 2024 Nov 22;38(2):127-134. doi: 10.1080/08998280.2024.2430153. eCollection 2025.

Abstract

INTRODUCTION

Bleeding from gastric varices (GV) is more drastic and associated with higher mortality than that from esophageal varices. There are multiple therapeutic approaches for GV bleeding. Although endoscopic cyanoacrylate glue injection (ECGI) is recommended as the first-line management for GV bleeding worldwide, its implementation in the US is limited. We conducted a survey among health care providers to examine attitudes and practice related to GV management.

METHODS

Collected data were cleaned using SPSS V24. Summary statistics and graphical analyses for continuous and categorical variables were used to describe the data. Continuous variables with a normal distribution are presented as mean ± standard deviation.

RESULTS

A total of 339 providers completed the survey, for a response rate of 16.95%. Nearly a quarter of respondents reported performing ECGI in patients with GV bleeding. Male healthcare providers (odds ratio [OR]: 2.1, 95% confidence interval [CI] = 1.22-3.75,  = 0.006), transplant hepatologists (OR: 2.6, 95% CI = 1.25-4.87,  = 0.019), and those working in hospitals with liver transplantation centers (OR: 2.5, 95% CI = 1.35-4.62,  = 0.002) were more likely to perform ECGI in GV bleeding cases. However, only gender was significant in the multivariate model.

CONCLUSIONS

Our results indicate the underutilization of ECGI in GV patients among US endoscopists. Key hurdles are lack of training and approval from the US Food and Drug Administration.

摘要

引言

胃静脉曲张(GV)出血比食管静脉曲张出血更为严重,且死亡率更高。治疗GV出血有多种方法。尽管内镜下注射氰基丙烯酸酯胶(ECGI)在全球范围内被推荐为治疗GV出血的一线方法,但其在美国的应用有限。我们对医疗服务提供者进行了一项调查,以研究与GV管理相关的态度和实践。

方法

使用SPSS V24对收集的数据进行清理。对连续变量和分类变量进行汇总统计和图形分析以描述数据。呈正态分布的连续变量以均值±标准差表示。

结果

共有339名提供者完成了调查,回复率为16.95%。近四分之一的受访者报告曾对GV出血患者实施ECGI。男性医疗服务提供者(比值比[OR]:2.1,95%置信区间[CI]=1.22 - 3.75,P = 0.006)、移植肝病学家(OR:2.6,95% CI = 1.25 - 4.87,P = 0.019)以及在设有肝移植中心的医院工作的人员(OR:2.5,95% CI = 1.35 - 4.62,P = 0.002)在GV出血病例中更有可能实施ECGI。然而,在多变量模型中只有性别具有统计学意义。

结论

我们的结果表明美国内镜医师对GV患者使用ECGI的情况不足。主要障碍是缺乏培训以及未获得美国食品药品监督管理局的批准。

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