Dunn Josie, Schifano Fabrizio, Dudley Ed, Arillotta Davide, Guirguis Amira
Pharmacy, Medical School, The Grove, Swansea University, Swansea SA2 8PP, UK.
Psychopharmacology, Drug Misuse and Novel Psychoactive Substances Research Unit, School of Life and Medical Sciences, University of Hertfordshire, Hatfield AL10 9AB, UK.
Brain Sci. 2025 Feb 10;15(2):172. doi: 10.3390/brainsci15020172.
BACKGROUND/OBJECTIVES: The misuse of veterinary drugs is a growing concern, with increasing evidence of their presence in illicit drug markets and their use as alternatives to traditional substances.
This study explores Reddit discussions on the misuse of veterinary drugs on Reddit, focusing on xylazine, carfentanil, medetomidine, pentobarbital, phenylbutazone, and acepromazine. Reddit was utilised for its abundant real-time data on users' thoughts and experiences with substance misuse. Through a combination of manual and Artificial Intelligence (AI)-driven thematic analysis, we examined posts and comments to explore patterns of misuse.
The themes analysed included adverse effects, polysubstance misuse, routes of administration, motivations for misuse, and methods of obtaining these drugs. Our findings revealed that xylazine, medetomidine, carfentanil, and pentobarbital exhibit significant potential for misuse, while phenylbutazone and acepromazine are not widely misused. Despite this, phenylbutazone and acepromazine have been identified as adulterants in the illicit drug supply in the United States. The most discussed themes included motivations for misuse, followed by public experiences and perceptions, as well as adverse effects.
The dual-method approach of combining manual interpretation with AI analysis allowed for a comprehensive understanding of social media discussions. This research highlights the importance of monitoring online platforms for early indicators of emerging drug trends, offering valuable insights to inform public health policies and intervention strategies. Impact Statement: This research highlights the growing public health risk posed by veterinary drug misuse, underscoring the need for enhanced monitoring, regulatory frameworks, and education to address their diversion into illicit markets. By leveraging social media as an early detection tool for emerging drug trends, our findings can inform targeted interventions.
背景/目的:兽药的滥用问题日益受到关注,越来越多的证据表明其出现在非法药物市场,并被用作传统药物的替代品。
本研究探讨了Reddit上关于兽药滥用的讨论,重点关注赛拉嗪、卡芬太尼、美托咪定、戊巴比妥、保泰松和乙酰丙嗪。选择Reddit是因为其拥有大量关于用户药物滥用想法和经历的实时数据。通过人工和人工智能驱动的主题分析相结合的方式,我们检查了帖子和评论,以探索滥用模式。
分析的主题包括不良反应、多药滥用、给药途径、滥用动机以及获取这些药物的方法。我们的研究结果表明,赛拉嗪、美托咪定、卡芬太尼和戊巴比妥存在显著的滥用潜力,而保泰松和乙酰丙嗪未被广泛滥用。尽管如此,保泰松和乙酰丙嗪已在美国非法药物供应中被确认为掺假物质。讨论最多的主题包括滥用动机,其次是公众经历和认知以及不良反应。
将人工解读与人工智能分析相结合的双方法途径能够全面理解社交媒体讨论。本研究强调了监测在线平台以获取新兴药物趋势早期指标的重要性,为制定公共卫生政策和干预策略提供了有价值的见解。影响声明:本研究突出了兽药滥用对公共卫生构成的日益严重风险,强调需要加强监测、监管框架和教育,以应对其流入非法市场的问题。通过将社交媒体作为新兴药物趋势的早期检测工具,我们的研究结果可为有针对性的干预措施提供参考。