一项评估孕期高血压与胎盘植入可能关联的Meta分析。
A Meta-Analysis to Assess the Probable Association of Hypertension During Pregnancy and Placenta Accreta.
作者信息
Imam Mohamed S, Meshari Abdularhman Alnaim Dina, Khalid Abdullah Alaraifi Renad, Salah Saleh Alabduljabbar Juman, Abdulrahman Mohammed Alhamed Alanoud, Mohammed Fayadh Alansari Asalah, Ali Alqarni Raghad Abdullah, Fahad Saleh Alotaibi Shouq, Zuwayyid Aali Alsufyani Dimah, Mohammed Abdullah Alzaidi Rana, Ali Hussain Mathkoor Shahad, Hameed Hamde Alotaibi Rawabi, Abdelrahim Mohamed E A, Mohamed Basma M E
机构信息
Department of Clinical Pharmacy, National Cancer Institute, Cairo University, Fom El Khalig Square, Kasr Al-Aini Street, Cairo 11796, Egypt.
College of Clinical Pharmacy, King Faisal University, Al Hofuf 31982, Al-Ahsa, Saudi Arabia.
出版信息
Medicina (Kaunas). 2025 Feb 8;61(2):297. doi: 10.3390/medicina61020297.
: A meta-analysis was conducted to assess the probable association of hypertension during pregnancy and placenta accreta (PA). : A systematic literature search was conducted up to November 2024, resulting in the identification of 10 studies encompassing 128,589 pregnant women. They reported associations between the possible impacts of hypertension during pregnancy and PA. The odds ratio (OR), with 95% confidence intervals (CIs), was computed to evaluate the possible association of hypertension during pregnancy and PA, utilizing a dichotomous approach with either a random or fixed-effect model. : No significant difference was found between hypertension during pregnancy and control (no hypertension during pregnancy) in the occurrence of PA (OR, 0.74; 95% CI, 0.52-1.04, = 0.08). Also, no significant difference was found between pregnant women with PA and control (no PA) in the occurrence of hypertension (OR, 1.15; 95% CI, 0.61-2.19, = 0.66). : Hypertension during pregnancy has no impact on the occurrence of PA, and vice versa. More research is desired to approve these outcomes.
进行了一项荟萃分析，以评估孕期高血压与胎盘植入（PA）之间可能存在的关联。截至2024年11月进行了系统的文献检索，共识别出10项研究，涉及128,589名孕妇。这些研究报告了孕期高血压的可能影响与胎盘植入之间的关联。采用随机或固定效应模型的二分法，计算了比值比（OR）及其95%置信区间（CI），以评估孕期高血压与胎盘植入之间的可能关联。在胎盘植入的发生率方面，孕期高血压与对照组（孕期无高血压）之间未发现显著差异（OR，0.74；95%CI，0.52 - 1.04，P = 0.08）。此外，在高血压的发生率方面，患有胎盘植入的孕妇与对照组（无胎盘植入）之间也未发现显著差异（OR，1.15；95%CI，0.61 - 2.19，P = 0.66）。孕期高血压对胎盘植入的发生没有影响，反之亦然。需要更多研究来证实这些结果。
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