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在低收入和中等收入国家接受治疗的创伤性脊髓损伤患者:出院后会怎样?

Patients with traumatic spinal injuries treated in a low- and middle-income country: what happens after discharge?

作者信息

Ikwuegbuenyi Chibuikem A, Zeoli Tyler, Waterkeyn François, Shayo Consolata, Joseph Julieth, Mwavika Rahel, Solanki Hiten, Okembo Arthur, Woodfield Julie, Willett Noah, Hussain Ibrahim, Shabani Hamisi K, Mangat Halinder S, Zuckerman Scott L, Härtl Roger

机构信息

1Department of Neurological Surgery, Och Spine at NewYork-Presbyterian Hospital, Weill Cornell Medicine, New York, New York.

2Department of Neurological Surgery, Vanderbilt University Medical Center, Nashville, Tennessee.

出版信息

Neurosurg Focus. 2025 Mar 1;58(3):E2. doi: 10.3171/2024.12.FOCUS24826.

Abstract

OBJECTIVE

Traumatic spinal injuries (TSIs) represent significant global health challenges, particularly in low- and middle-income countries (LMICs). In a cohort of patients with TSI from a major East African center, the authors sought to address long-term outcomes after hospital discharge through the following objectives: 1) describe who was successfully contacted after hospital discharge, 2) report posthospital complications, and 3) assess predictors of successful posthospital contact and posthospital complications.

METHODS

An institutional TSI registry of patients treated from 2016 to 2021 was the source of patients and contact methods. Telephone calls were made to the primary telephone number between June 2022 and May 2023, and a subjective neurological assessment was performed using a questionnaire. The study outcomes were successful posthospital contact and postdischarge complications. Predictors of each outcome were assessed through univariable and multivariable logistic regression.

RESULTS

Of the 466 TSI patients treated from 2016 to 2021, 40.6% were successfully contacted at a median follow-up period of 29 months. Their median age was 34 years, and most patients were male (n = 400, 85.8%). Among those contacted, 84.8% experienced postdischarge complications, including muscle spasticity (n = 89, 61.4%), pressure ulcers (n = 52, 35.9%), and death (n = 39, 21.2%). Most patients reported a perceived improvement in their neurological status. Key factors predicting successful contact included undergoing surgery, involvement in road traffic accidents, and more recent hospital admission dates following TSI (2019-2021). Employment postinjury was associated with fewer complications (OR 0.20, 95% CI 0.04-0.76; p = 0.029). American Spinal Injury Association Impairment Scale (AIS) grade A at discharge was associated with a significantly increased mortality risk compared with AIS grades B-E (OR 15.58, 95% CI 5.80-50.46; p < 0.001).

CONCLUSIONS

This is one of few studies to report on posthospital follow-up using telephone contact for TSI in an LMIC. Among the contactable patients, there were high rates of morbidity and mortality and low rates of employment, showing the considerable medical, social, and economic impact of TSI in this young population and the need for rehabilitation and support services postdischarge.

摘要

目的

创伤性脊髓损伤(TSIs)是全球重大的健康挑战,在低收入和中等收入国家(LMICs)尤为如此。在东非一个主要中心的一组创伤性脊髓损伤患者中,作者试图通过以下目标来探讨出院后的长期结局:1)描述出院后成功取得联系的患者情况,2)报告出院后并发症,3)评估出院后成功取得联系及出院后并发症的预测因素。

方法

2016年至2021年接受治疗的患者的机构创伤性脊髓损伤登记册是患者及联系方法的来源。2022年6月至2023年5月期间拨打主要电话号码,并使用问卷进行主观神经学评估。研究结局为出院后成功取得联系及出院后并发症。通过单变量和多变量逻辑回归评估各结局的预测因素。

结果

在2016年至2021年接受治疗的466例创伤性脊髓损伤患者中,在中位随访期29个月时,40.6%的患者成功取得联系。他们的中位年龄为34岁,大多数患者为男性(n = 400,85.8%)。在取得联系的患者中,84.8%经历了出院后并发症,包括肌肉痉挛(n = 89,61.4%)、压疮(n = 52,35.9%)和死亡(n = 39,21.2%)。大多数患者报告感觉神经状况有所改善。预测成功取得联系的关键因素包括接受手术、卷入道路交通事故以及创伤性脊髓损伤后更近的入院日期(2019 - 2021年)。受伤后就业与较少的并发症相关(比值比0.20,95%置信区间0.04 - 0.76;p = 0.029)。出院时美国脊髓损伤协会损伤量表(AIS)A级与AIS B - E级相比,死亡风险显著增加(比值比15.58,95%置信区间5.80 - 50.46;p < 0.001)。

结论

这是少数几项报告在低收入和中等收入国家通过电话联系对创伤性脊髓损伤患者进行出院后随访的研究之一。在可联系到的患者中,发病率和死亡率较高,就业率较低,这表明创伤性脊髓损伤对这一年轻人群具有相当大的医疗、社会和经济影响,以及出院后对康复和支持服务的需求。

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