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miR-429 RNA therapy as generic strategy to protect against photoreceptor loss.

作者信息

Wijnholds Jan

机构信息

Department of Ophthalmology, Leiden University Medical Center (LUMC), Albinusdreef 2, 2333 ZA Leiden, the Netherlands.

Netherlands Institute for Neuroscience, an Institute of the Royal Netherlands Academy of Arts and Sciences (KNAW), Meibergdreef 47, 1105 BA Amsterdam, the Netherlands.

出版信息

Mol Ther Nucleic Acids. 2025 Feb 15;36(1):102477. doi: 10.1016/j.omtn.2025.102477. eCollection 2025 Mar 11.

Abstract
摘要

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本文引用的文献

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high-content screening reveals miR-429 as a protective molecule in photoreceptor degeneration.
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Restoration of Rod-Derived Metabolic and Redox Signaling to Prevent Blindness.
Cold Spring Harb Perspect Med. 2024 Nov 1;14(11):a041284. doi: 10.1101/cshperspect.a041284.
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miR-181a/b downregulation: a mutation-independent therapeutic approach for inherited retinal diseases.
EMBO Mol Med. 2022 Nov 8;14(11):e15941. doi: 10.15252/emmm.202215941. Epub 2022 Oct 4.
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Inhibition of MicroRNA 6937 Delays Photoreceptor and Vision Loss in a Mouse Model of Retinitis Pigmentosa.
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Calpain Activation Is the Major Cause of Cell Death in Photoreceptors Expressing a Rhodopsin Misfolding Mutation.
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