Shamoun Shaimaa, Ahmad Muayyad
Oncology Hospital, Al-Bashir Hospitals, Jordanian Ministry of Health, Amman, Jordan.
Jordan University, Faculty of Nursing, Amman, Jordan.
Eur J Breast Health. 2025 Mar 25;21(2):122-131. doi: 10.4274/ejbh.galenos.2025.2024-12-11. Epub 2025 Mar 3.
This study aimed to compare the incidence of breast cancer-related lymphedema (BCRL) between a control group and women with breast cancer who underwent complete decongestive therapy (CDT). Moreover, the quality of life (QOL) was assessed and compared between the intervention group receiving CDT and the control group.
A quasi-experimental design with a purposeful sampling approach was employed for enrollment. All participants had undergone surgical interventions, specifically axillary lymph node dissection (ALND), for breast cancer at a public healthcare facility between February and July 2023. Over an 18-week period, the intervention group followed a structured CDT protocol, which included receiving skin care instructions, undergoing 30-minute manual lymphatic drainage sessions on the affected arm, wearing compression sleeves for 12 hours daily, and participating in exercise sessions three times per week.
In total 180 women, 90 in the CDT group and 90 controls were recruited. The CTD intervention group experienced a notable reduction in the incidence of BCRL development and a significant improvement in QOL across the three assessment times (baseline vs week 9 and week 9 vs week 18) during the study (<0.001). In contrast, the control group showed an increased rate of BCRL development and a significant decline in QOL when comparing the same three time points (<0.001).
Implementing CDT within the first year following ALND led to a significant reduction in the incidence of BCRL and a marked improvement in the QOL for women with who underwent surgery and ALND for breast cancer.
本研究旨在比较对照组与接受完全减压疗法(CDT)的乳腺癌女性患者中与乳腺癌相关的淋巴水肿(BCRL)的发生率。此外,对接受CDT的干预组和对照组的生活质量(QOL)进行评估和比较。
采用有目的抽样方法的准实验设计进行入组。所有参与者均于2023年2月至7月在一家公共医疗机构接受了乳腺癌手术干预,具体为腋窝淋巴结清扫术(ALND)。在18周的时间里,干预组遵循结构化的CDT方案,包括接受皮肤护理指导、对患侧手臂进行30分钟的手动淋巴引流治疗、每天佩戴压力袖套12小时以及每周参加三次锻炼课程。
共招募了180名女性,其中CDT组90名,对照组90名。在研究期间的三个评估时间点(基线与第9周、第9周与第18周),CTD干预组的BCRL发生率显著降低,生活质量显著改善(<0.001)。相比之下,对照组在相同的三个时间点进行比较时,BCRL发生率上升,生活质量显著下降(<0.001)。
在ALND后的第一年内实施CDT可显著降低接受乳腺癌手术和ALND的女性的BCRL发生率,并显著改善其生活质量。