Wiss David A, LaFata Erica M
Department of Community Health Sciences, Fielding School of Public Health, University of California Los Angeles, 650 Young Drive South, Los Angeles, CA, 90095, USA.
Drexel University Center for Weight Eating and Lifestyle Science, 3201 Chestnut Street, Philadelphia, PA, 19104, USA.
Appetite. 2025 Apr 1;208:107938. doi: 10.1016/j.appet.2025.107938. Epub 2025 Mar 2.
Adverse childhood experiences (ACEs), such as abuse, neglect, or household violence, have been identified as significant risk factors for a multitude of physical and psychological conditions, motivating research to identify contributing mechanisms and conditions. Substantial evidence exists that supports strong associations between ACEs and symptoms of post-traumatic stress disorder (PTSD), eating disorders (EDs), and addictive disorders. Recent research has also elucidated a link between ACEs and ultra-processed food addiction (UPFA), a clinical presentation resembling a substance use disorder with ultra-processed foods (UPFs; e.g., pastries, packaged snacks, sweetened beverages). Yet, no research to our knowledge has explored causal mediation pathways between ACEs, consumption patterns of UPFs, and symptoms of PTSD, UPFA, and ED. In a sample of 304 adults seeking dietary counseling in a private practice specializing in mental health nutrition, this study conducted mediation analyses and structural equation modeling to test a conceptual model of the hypothesized contributions of UPF intake and UPFA in explaining the relationships between ACEs with symptoms of PTSD and ED. Symptoms of PTSD fully mediated (99.4%) the positive relationship between ACEs and ED symptoms and 51.0% of the ACE-UPFA association. Greater UPF consumption frequency mediated 23.7% of the positive relationship between ACEs and UPFA symptoms, and UPFA symptoms mediated 73.8% of the positive relationship between UPF intake and ED symptomology. Relatedly, symptoms of UPFA explained 46.0% of the positive association between symptoms of PTSD and indicators of ED pathology. Structural equation modeling indicated significant associations of all hypothesized relationships when analyzed simultaneously. This study found that the influences of UPF consumption and UPFA represent a blind spot in current trauma-informed treatment approaches for disordered eating.
童年不良经历(ACEs),如虐待、忽视或家庭暴力,已被确认为多种身体和心理状况的重要风险因素,这促使人们开展研究以确定其作用机制和相关状况。大量证据表明,ACEs与创伤后应激障碍(PTSD)、饮食失调(EDs)和成瘾性障碍的症状之间存在密切关联。最近的研究还阐明了ACEs与超加工食品成瘾(UPFA)之间的联系,超加工食品成瘾是一种临床表现,类似于对超加工食品(UPFs;如糕点、包装零食、含糖饮料)的物质使用障碍。然而,据我们所知,尚无研究探讨ACEs、UPFs消费模式与PTSD、UPFA和ED症状之间的因果中介途径。在一个由304名在一家专门从事心理健康营养的私人诊所寻求饮食咨询的成年人组成的样本中,本研究进行了中介分析和结构方程建模,以检验一个概念模型,该模型假设UPF摄入量和UPFA在解释ACEs与PTSD和ED症状之间的关系中所起的作用。PTSD症状完全中介了(99.4%)ACEs与ED症状之间的正相关关系以及ACE-UPFA关联的51.0%。更高的UPF消费频率中介了ACEs与UPFA症状之间正相关关系的23.7%,而UPFA症状中介了UPF摄入量与ED症状之间正相关关系的73.8%。相关地,UPFA症状解释了PTSD症状与ED病理学指标之间正相关关系的46.0%。结构方程建模表明,当同时分析所有假设关系时,它们之间存在显著关联。本研究发现,UPF消费和UPFA的影响代表了当前饮食失调的创伤知情治疗方法中的一个盲点。