Two different variants of the same tropomyosin polypeptide in clones from GM1386 human skin fibroblasts.

A new protein observed in two-dimensional electrophoresis patterns of proteins from the human skin fibroblast line GM1386 has been identified as a charge and molecular-weight variant of the type of tropomyosin found in smooth muscle (Tm:3). This is the second variant of Tm:3 found in GM1386 and represents a second site mutation in one of the genes coding for Tm:3.