Rajesh E, Dhivyadharshini S, Babu N Aravindha, Ramya C
Department of Oral Pathology and Microbiology, Sree Balaji Dental College and Hospitals (SBDCH), Oral Cancer Prevention Awareness and Research (COCPAR), Bharath University (BIHER), Chennai, Tamil Nadu, India.
J Pharm Bioallied Sci. 2024 Dec;16(Suppl 5):S4921-S4924. doi: 10.4103/jpbs.jpbs_1291_24. Epub 2025 Jan 30.
Dentigerous cysts frequently develop as odontogenic cysts in the oral cavity that can occasionally progress to neoplasms. Tumor from dentigerous cysts is uncommon, with only 42 occurrences documented in the literature. This case report describes a 73-year-old male who developed primary intraosseous squamous cell carcinoma after a dentigerous cyst. The dental practitioner should have knowledge of the potential for malignant transformation in asymptomatic dentigerous cysts and ensure thorough follow-up. Even if the lesion appears benign, it is recommended to perform a complete histological investigation. Histopathological investigations have revealed malignancies in the follicle that surrounds the dental crown. While malignant lesion formation is uncommon, it should be considered a differential diagnosis in appropriate circumstances.
含牙囊肿常作为口腔中的牙源性囊肿出现,偶尔会发展为肿瘤。含牙囊肿恶变罕见,文献中仅有42例记载。本病例报告描述了一名73岁男性,其在含牙囊肿后发生了原发性骨内鳞状细胞癌。牙科医生应了解无症状含牙囊肿恶变的可能性,并确保进行全面随访。即使病变看似良性,也建议进行完整的组织学检查。组织病理学检查已揭示围绕牙冠的滤泡中有恶性肿瘤。虽然恶性病变形成罕见,但在适当情况下应将其视为鉴别诊断。