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尿布中的邻苯二甲酸盐:婴儿皮肤暴露及环境中邻苯二甲酸盐释放的评估。

Phthalates in diapers: Assessment of dermal exposure of babies and environmental phthalate release.

作者信息

Gül Hatice Kübra, Tanrikulu Samiye, Akcetin Merve Ozkaleli, Daglioglu Nebile, Goren İsmail Ethem, Kurt Karakus Perihan Binnur

机构信息

Department of Environmental Engineering, Faculty of Engineering and Natural Sciences, Bursa Technical University, Bursa, Türkiye.

Institute of Forensic Sciences, Dept. of Forensic Toxicology, Ankara University, Ankara, Türkiye.

出版信息

Chemosphere. 2025 May;376:144283. doi: 10.1016/j.chemosphere.2025.144283. Epub 2025 Mar 11.

Abstract

In the current study the presence of selected phthalates in diapers used in Türkiye and release of phthalates through baby diapers into waste disposal sites were investigated. Targeted phthalates were analyzed in three different layers of a total of 39 diaper samples sold in the Turkish market. Butyl benzyl phthalate (BBP), Diethyl phthalate (DEP) and Di-n-butyl phthalate (DnBP) were detected in all three layers of diapers. Based on the results obtained, diaper-originated dermal exposure of babies (0-2.5 years) to phthalates and environmental phthalate loading amounts due to disposal of diapers were calculated. Deterministic and probabilistic risk assessment showed that MOE and MOE values were higher than 1000, indicating that exposure to the phthalates detected in these diapers did not pose a risk for babies. Additionally, the amount of phthalates loading due to the disposal of diapers to the environment ranges from 13.0 to 407 kg year depending on the diaper brand. Based on the estimated number of newborns and infants, the highest phthalate release was estimated to be in Istanbul province (71.6 kg year), while, the lowest phthalate release was estimated to be in Tunceli province (0.011 kg year).

摘要

在当前研究中,对土耳其使用的尿布中特定邻苯二甲酸盐的存在情况以及邻苯二甲酸盐通过婴儿尿布释放到废物处理场所的情况进行了调查。在土耳其市场销售的总共39个尿布样品的三个不同层中分析了目标邻苯二甲酸盐。在尿布的所有三层中均检测到邻苯二甲酸丁苄酯(BBP)、邻苯二甲酸二乙酯(DEP)和邻苯二甲酸二正丁酯(DnBP)。根据所得结果,计算了婴儿(0至2.5岁)因使用尿布而经皮肤接触邻苯二甲酸盐的情况以及因尿布处理导致的环境中邻苯二甲酸盐负荷量。确定性和概率性风险评估表明,MOE和MOE值高于1000,这表明接触这些尿布中检测到的邻苯二甲酸盐对婴儿没有风险。此外,根据尿布品牌不同,因尿布处理而释放到环境中的邻苯二甲酸盐量为每年13.0至407千克。根据估计的新生儿和婴儿数量,估计邻苯二甲酸盐释放量最高的是伊斯坦布尔省(每年71.6千克),而最低的是通杰利省(每年0.011千克)。

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