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诊断性鼻内镜检查和计算机断层扫描在成人慢性鼻-鼻窦炎中的作用:临床相关性研究

The Role of Diagnostic Nasal Endoscopy and Computed Tomography Scan in Chronic Rhinosinusitis in Adults: A Study of Clinical Correlation.

作者信息

Acharia Kuldeep, Thakur Pooja, Dasgupta Puspen, Gon Sabyasachi, Mukherjee Dharitri, Dandapath Anwesha, Dey Apu, Patra Abhishek

机构信息

Department of Otorhinolaryngology, IQ City Medical College and Hospital, IQ City Road, Durgapur, Dist- Burdwan, WB 713206 India.

出版信息

Indian J Otolaryngol Head Neck Surg. 2025 Mar;77(3):1552-1557. doi: 10.1007/s12070-025-05376-w. Epub 2025 Feb 8.

Abstract

Chronic rhinosinusitis (CRS) is an inflammatory disease affecting the paranasal sinuses (PNS) with a lifetime prevalence of approximately 15%, impacting about 1 in 8 Indians. The condition is rapidly evolving, with an exponential increase in cases due to rising atmospheric pollution and exposure to various allergens. CRS is one of the most common reasons for ENT consultations, significantly impairing patients' quality of life. Defined by inflammation lasting more than 12 weeks, CRS diagnosis relies on EPOS criteria using endoscopy and computed tomography (CT) scans. CRS affects about 11% of the global population and ranks among the top 10 costliest health conditions, highlighting the need for cost-effective and accessible diagnostic tools. This observational study was conducted in a tertiary care hospital and included 53 CRS patients (age 18-70 years) undergoing diagnostic nasal endoscopy (DNE) and non-contrast CT. The Lund-Mackay and Lund-Kennedy scores evaluated CT and DNE findings, respectively. Statistical analysis included descriptive, Mann-Whitney, chi-square tests, and Spearman correlation. Nasal obstruction (98.11%) predominated, with CT revealing maxillary sinus involvement (52.83%) and common anatomical variations such as a deviated nasal septum. DNE identified edema (66.03%) and nasal polyps (15.1%). A strong correlation (0.866) between Lund-Kennedy and Lund-Mackay scores validated DNE. DNE showed 91.31% sensitivity, 71.46% specificity, and 86.44% diagnostic accuracy versus CT. DNE proves to be reliable in CRS assessment, aligning well with CT findings. It offers a cost-effective initial evaluation and management option, crucial in resource-limited settings.

摘要

慢性鼻-鼻窦炎(CRS)是一种影响鼻窦(PNS)的炎症性疾病,终生患病率约为15%,约每8名印度人中就有1人受其影响。由于大气污染加剧和接触各种过敏原,该疾病正在迅速演变,病例呈指数级增长。CRS是耳鼻喉科门诊最常见的原因之一,严重损害患者的生活质量。CRS定义为炎症持续超过12周,其诊断依赖于使用内窥镜检查和计算机断层扫描(CT)的欧洲鼻窦炎和鼻息肉诊疗意见书(EPOS)标准。CRS影响全球约11%的人口,是最昂贵的十大健康疾病之一,这凸显了对具有成本效益且可及的诊断工具的需求。本观察性研究在一家三级医院进行,纳入了53例接受诊断性鼻内窥镜检查(DNE)和非增强CT的CRS患者(年龄18至70岁)。Lund-Mackay和Lund-Kennedy评分分别评估CT和DNE的检查结果。统计分析包括描述性统计、曼-惠特尼检验、卡方检验和斯皮尔曼相关性分析。鼻塞(98.11%)最为常见,CT显示上颌窦受累(52.83%)以及常见的解剖变异,如鼻中隔偏曲。DNE发现水肿(66.03%)和鼻息肉(15.1%)。Lund-Kennedy评分与Lund-Mackay评分之间的强相关性(0.866)验证了DNE的可靠性。与CT相比,DNE的敏感性为91.31%,特异性为71.46%,诊断准确性为86.44%。在CRS评估中,DNE被证明是可靠的,与CT检查结果高度吻合。它提供了一种具有成本效益的初始评估和管理选择,这在资源有限的环境中至关重要。

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