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评估CELF-5筛查测试和文兰适应行为量表第三版用于识别自闭症和注意力缺陷多动障碍中的语言困难情况。

Evaluating the CELF-5 Screening Test and Vineland-3 for Identifying Language Difficulties in Autism and Attention Deficit Hyperactivity Disorder.

作者信息

Mohanakumar Sindhu Vishnu Priya, Brignell Amanda, Moses Mia, Kallady Kathryn, Bellgrove Mark A, Johnson Beth P

机构信息

Turner Institute for Brain and Mental Health, School of Psychological Sciences Monash University, Melbourne, Australia.

Department of Paediatrics, Monash University, Melbourne, Australia.

出版信息

Autism Res. 2025 Apr;18(4):857-869. doi: 10.1002/aur.70021. Epub 2025 Mar 18.

Abstract

Language screening tools are frequently used to identify children with potential undiagnosed language difficulties. These difficulties are more prevalent in autistic children and those with attention deficit hyperactivity disorder (ADHD) compared to neurotypical peers. Despite the widespread use of tools like the Clinical Evaluation of Language Fundamentals, Fifth Edition Screening Test (CELF-5 Screener) and the Vineland Adaptive Behavior Scales, Third Edition (Vineland-3), their sensitivity and specificity for this population have not been empirically validated. This study aimed to evaluate the screening accuracy of the CELF-5 Screener and Vineland-3 in children diagnosed with autism and/or ADHD and compare their performance to the gold standard measure. The sample consisted of 132 participants (n  = 25; n  = 29, and n  = 78; M  = 9.6; % male = 59) from the Monash Autism-ADHD Genetics and Neurodevelopment Project. The sensitivity, specificity, positive predictive value, and negative predictive value of the CELF-5 Screener and Vineland-3 receptive and expressive language subdomain scores were compared against those of the clinician-administered CELF-5 receptive and expressive language composite scores. The screening accuracy of each tool was further evaluated through Receiver Operating Characteristic analyses and calculations of Youden's J statistic. The CELF-5 Screener demonstrated poor sensitivity for receptive language difficulties (35.6%) while demonstrating high specificity (95.3%). Similarly, for expressive language difficulties, the sensitivity was low (37.9%), and the specificity was high (91.1%). The Vineland-3 showed high sensitivity (93.3%) but low specificity (48%) for expressive language difficulties and inadequate sensitivity (80.9%) and specificity (22.4%) for receptive language difficulties. Both the CELF-5 Screener and Vineland-3 may miss a significant number of children with co-occurring language difficulties related to autism and/or ADHD. Examiners must understand these tools' strengths and limitations, especially when assessing neurodivergent children whose language development might not follow a normative trajectory.

摘要

语言筛查工具经常被用于识别可能存在未被诊断出的语言困难的儿童。与发育正常的同龄人相比,这些困难在自闭症儿童和患有注意力缺陷多动障碍(ADHD)的儿童中更为普遍。尽管像《语言基本能力临床评估第五版筛查测试》(CELF - 5筛查测试)和《文兰适应行为量表第三版》(文兰 - 3)这样的工具被广泛使用,但它们针对这一人群的敏感性和特异性尚未得到实证验证。本研究旨在评估CELF - 5筛查测试和文兰 - 3在被诊断为自闭症和/或ADHD的儿童中的筛查准确性,并将它们的表现与金标准测量方法进行比较。样本包括来自莫纳什自闭症 - ADHD遗传学与神经发育项目的132名参与者(n = 25;n = 29;n = 78;平均年龄M = 9.6岁;男性占比59%)。将CELF - 5筛查测试和文兰 - 3接受性和表达性语言子领域得分的敏感性、特异性、阳性预测值和阴性预测值与临床医生实施的CELF - 5接受性和表达性语言综合得分进行了比较。通过绘制受试者工作特征曲线分析和计算尤登指数进一步评估了每种工具的筛查准确性。CELF - 5筛查测试对接受性语言困难的敏感性较差(35.6%),而特异性较高(95.3%)。同样,对于表达性语言困难,敏感性较低(37.9%),特异性较高(91.1%)。文兰 - 3对表达性语言困难表现出高敏感性(93.3%)但低特异性(48%),对接受性语言困难的敏感性(80.9%)和特异性(22.4%)不足。CELF - 5筛查测试和文兰 - 3都可能遗漏大量与自闭症和/或ADHD相关的同时存在语言困难的儿童。检查人员必须了解这些工具的优势和局限性,尤其是在评估语言发展可能不遵循正常轨迹的神经发育异常儿童时。

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