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用组织学测量法评估干燥氢氧化铝凝胶对大鼠醋酸溃疡的促愈合作用。

Healing-promoting action of dried aluminium hydroxide gel evaluated by the method of histological measurements in acetic acid ulcer of rats.

作者信息

Ito M, Fujii A, Suzuki Y

出版信息

Jpn J Pharmacol. 1985 Apr;37(4):401-4. doi: 10.1254/jjp.37.401.

Abstract

The effects of dried aluminium hydroxide gel on the healing of rat acetic acid ulcer were studied in comparison to those of propantheline bromide by the method of histological measurements. Dried aluminium hydroxide gel not only decreased the macroscopic ulcer index and the defective area in the ulcerated region but also increased the decreasing index of exposed ulcer floor and the mucosal regeneration index without affecting the thickness of the ulcer base and the development index of collagen fibers. However, propantheline bromide did not have any beneficial effects.

摘要

采用组织学测量方法,比较了干燥氢氧化铝凝胶与溴丙胺太林对大鼠乙酸溃疡愈合的影响。干燥氢氧化铝凝胶不仅降低了宏观溃疡指数和溃疡区域的缺损面积,还提高了溃疡底部暴露的减少指数和黏膜再生指数,而不影响溃疡底部的厚度和胶原纤维的发育指数。然而,溴丙胺太林没有任何有益效果。

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