McCullough John, Sundquist Wesley I
Department of Biochemistry, University of Utah, Salt Lake City, UT, USA.
Nat Struct Mol Biol. 2025 Mar;32(3):414-417. doi: 10.1038/s41594-025-01511-x.
Three papers show that Vipp1, a plastid ESCRT-III protein, can form sheets, spirals and regular polygons on flat membranes and tubulate the membranes within stacked rings and helices. This work provides a framework for how Vipp1 can deliver lipids for thylakoid membrane biogenesis and protect and repair the membranes during photosynthesis.
三篇论文表明,Vipp1(一种质体ESCRT-III蛋白)可在平面膜上形成片层、螺旋结构和规则多边形,并使堆叠的环和螺旋结构内的膜形成管状。这项工作为Vipp1如何为类囊体膜生物合成提供脂质以及在光合作用过程中保护和修复膜提供了一个框架。