Azimi Ali, Jafari Mohammad Reza, Namvar Ehsan, Masihpour Nasrin, Meshksar Shadi
Poostchi Ophthalmology Research Center, Department of Ophthalmology, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran.
Shiraz University of Medical Sciences, Shiraz, Iran.
BMC Res Notes. 2025 Mar 18;18(1):116. doi: 10.1186/s13104-025-07116-3.
This study was designed to assess the efficacy of using povidone-iodine (PVI) 10% and levofloxacin 0.5% about one hour before cataract surgery in minimizing aqueous contamination compared with using PVI 10%. The intervention group received three drops of mixed povidone-iodine and levofloxacin (PVI/Levofloxacin) solution one hour before surgery. After making the corneal incision in cataract surgery, 0.1 cc aqueous humor sample was taken and sent for culture. We compared the intervention group and control group using t-test and chi-square test in SPSS 25(Chicago IL, USA). 147 eyes of 147 patients were analyzed. The intervention and control groups consisted of 72 and 75 patients, respectively. The Control group showed significantly more positive cultures (16 cultures: 22.2%). the intervention group had four positive cultures (5.3%). (P-value = 0.005). Topical levofloxacin 0.5% and povidone-iodine 10% mixture showed promising results in reducing the number of bacteria in the aqueous humor.
本研究旨在评估在白内障手术前约一小时使用10%聚维酮碘（PVI）和0.5%左氧氟沙星与单独使用10%聚维酮碘相比，在减少房水污染方面的疗效。干预组在手术前一小时滴入三滴混合的聚维酮碘和左氧氟沙星（PVI/左氧氟沙星）溶液。在白内障手术中制作角膜切口后，采集0.1 cc房水样本并送去培养。我们在美国伊利诺伊州芝加哥市的SPSS 25中使用t检验和卡方检验对干预组和对照组进行比较。分析了147例患者的147只眼睛。干预组和对照组分别由72例和75例患者组成。对照组的培养阳性结果明显更多（16例培养阳性：22.2%）。干预组有4例培养阳性（5.3%）。（P值 = 0.005）。局部使用0.5%左氧氟沙星和10%聚维酮碘混合物在减少房水中细菌数量方面显示出有前景的结果。
