Agarwal Sumeet, Mistry Laresh N, Kamath Shamika, Thorat Rohit, Gupta Bharat, Kondkari Saba
Prosthodontics, Bharati Vidyapeeth (Deemed to be University) Dental College and Hospital, Navi Mumbai, IND.
Pediatric and Preventive Dentistry, Bharati Vidyapeeth (Deemed to be University) Dental College and Hospital, Navi Mumbai, IND.
Cureus. 2025 Feb 15;17(2):e79030. doi: 10.7759/cureus.79030. eCollection 2025 Feb.
Bioprinting is revolutionizing the field of dentistry by enabling the fabrication of complex dental tissues using advanced techniques like inkjet, extrusion-based, and laser-assisted bioprinting. These methods allow for the precise placement of cells and materials to regenerate dental pulp, periodontal tissues, alveolar bone, and temporomandibular joint structures. Hydrogels, composite bioinks, and cell-laden bioinks play a crucial role in scaffold formation and improving cell viability. Preclinical models have demonstrated the potential of bioprinting for tissue regeneration and dental implants, with early clinical trials showing promising results. However, challenges remain, including scalability, material selection, immune response, and regulatory approval. Future advancements in multi-material bioprinting, real-time monitoring, and personalized treatment approaches will expand clinical applications of bioprinting, driving innovation in oral healthcare and improving patient outcomes.
生物打印正在彻底改变牙科领域，它能够利用喷墨、挤出式和激光辅助生物打印等先进技术制造复杂的牙齿组织。这些方法允许精确放置细胞和材料，以再生牙髓、牙周组织、牙槽骨和颞下颌关节结构。水凝胶、复合生物墨水和载细胞生物墨水在支架形成和提高细胞活力方面起着至关重要的作用。临床前模型已经证明了生物打印在组织再生和牙种植体方面的潜力，早期临床试验显示出了有希望的结果。然而，挑战依然存在，包括可扩展性、材料选择、免疫反应和监管批准。多材料生物打印、实时监测和个性化治疗方法的未来进展将扩大生物打印的临床应用，推动口腔医疗保健领域的创新并改善患者治疗效果。
