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非骨水泥型初次全髋关节置换术中第三代陶瓷对陶瓷轴承的长期疗效:一项25年生存分析

Long-Term Outcomes of Third-Generation Ceramic-on-Ceramic Bearings in Cementless Primary Total Hip Arthroplasty: A 25-Year Survival Analysis.

作者信息

Heimann Alexander F, Swartz Gabrielle N, Bains Sandeep S, Dubin Jeremy A, Katanbaf Reza, Delanois Ronald E, Murphy Stephen B

机构信息

Department of Orthopaedic Surgery and Traumatology, HFR-Cantonal Hospital, University of Fribourg, Fribourg, Switzerland; Center for Computer Assisted and Reconstructive Surgery, New England Baptist Hospital, Boston, Massachusetts.

The Rubin Institute for Advanced Orthopedics, Lifebridge Health, Sinai Hospital of Baltimore, Baltimore, Maryland.

出版信息

J Arthroplasty. 2025 Aug;40(8S1):S243-S249. doi: 10.1016/j.arth.2025.03.029. Epub 2025 Mar 17.

Abstract

BACKGROUND

The demand for total hip arthroplasty (THA) in younger patients, particularly those under 65 years, has increased markedly in recent years. Ceramic-on-ceramic (CoC) bearings offer promising benefits, including reduced wear and osteolysis, with excellent short- to mid-term survival. However, long-term data on their performance in younger populations remain limited. This study aimed to investigate: (1) overall implant survival, (2) complications and reasons for revision, and (3) patient-reported outcomes at long-term follow-up after primary THA with third-generation CoC bearings.

METHODS

A retrospective analysis was performed on 231 patients (294 hips) who underwent cementless THA with third-generation CoC bearings between May 1999 and September 2004. The mean age at surgery was 50 years (range, 17 to 76). Clinical and radiographic outcomes were assessed at a minimum follow-up of 10 years, and the mean follow-up was 17 years (range, 10 to 25). Overall, 87 patients (108 hips, 38%) were lost to follow-up, leaving a total of 145 patients (186 hips) for further analysis. Kaplan-Meier survival analysis was used to estimate implant survival, with implant revision for any reason defined as a primary end point. Complications, reasons for revision, and patient-reported outcomes (Merle d'Aubigné-Postel score) were also evaluated.

RESULTS

Kaplan-Meier analysis demonstrated an implant survival rate of 93% at 25 years. At long-term follow-up, 12 hips (6.5%) required revision for either bearing failure (six hips), acetabular component failure (four hips), or femoral component failure (two hips). There were six cases of hip squeaking (3.2%) reported, none requiring revision. Functional outcomes improved significantly, with mean Merle d'Aubigné-Postel scores rising from 10.7 preoperatively to 17.6 at the final follow-up. Radiographic evaluations showed no cases of osteolysis or loosening.

CONCLUSIONS

Third-generation CoC bearings in cementless THA offer excellent long-term survival, low complication rates, and good to excellent functional outcomes, highlighting their durability and performance over a 25-year period.

摘要

背景

近年来,年轻患者,尤其是65岁以下患者对全髋关节置换术(THA)的需求显著增加。陶瓷对陶瓷(CoC)轴承具有诸多潜在益处,包括减少磨损和骨溶解,短期至中期生存率良好。然而,关于其在年轻人群中性能的长期数据仍然有限。本研究旨在调查:(1)整体植入物生存率;(2)并发症及翻修原因;(3)初次THA使用第三代CoC轴承进行长期随访时患者报告的结果。

方法

对1999年5月至2004年9月期间接受第三代CoC轴承非骨水泥THA的231例患者(294髋)进行回顾性分析。手术时的平均年龄为50岁(范围17至76岁)。在至少10年的随访中评估临床和影像学结果,平均随访时间为17年(范围10至25年)。总体而言,87例患者(108髋,38%)失访,剩余145例患者(186髋)进行进一步分析。采用Kaplan-Meier生存分析来估计植入物生存率,将因任何原因进行植入物翻修定义为主要终点。还评估了并发症、翻修原因以及患者报告的结果(Merle d'Aubigné-Postel评分)。

结果

Kaplan-Meier分析显示25年时植入物生存率为93%。在长期随访中,12髋(6.5%)因轴承故障(6髋)、髋臼组件故障(4髋)或股骨组件故障(2髋)需要翻修。报告了6例髋关节摩擦音(3.2%),均无需翻修。功能结果显著改善,Merle d'Aubigné-Postel平均评分从术前的10.7提高到最后随访时的17.6。影像学评估未发现骨溶解或松动病例。

结论

非骨水泥THA中的第三代CoC轴承具有出色的长期生存率、低并发症发生率以及良好至优异的功能结果,突出了其在25年期间的耐用性和性能。

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