Shi Li-Ke, Cai Xian-Feng, He Jian-Qing, Wang Yu-Hai
Department of Neurosurgery, Wuxi Clinical College of Anhui Medical University, Wuxi 214000, Jiangsu Province, China.
Department of Neurosurgery, Anhui Medical University Fifth Clinical Medical College, Hefei 230031, Anhui Province, China.
World J Psychiatry. 2025 Mar 19;15(3):100565. doi: 10.5498/wjp.v15.i3.100565.
Intracranial aneurysms, characterized by focal arterial wall dilation, pose significant neurosurgical challenges due to their potential for rupture and hemorrhage, leading to severe clinical outcomes, including fatality. Patients often experience profound psychological and social impacts, such as depression, anxiety, and cognitive impairment, affecting their quality of life. Rapid progression and high mortality necessitate timely intervention. Advances in neurosurgical techniques, including microscopic surgery and neuroendoscopy, offer distinct advantages. Microscopic surgery provides precision and direct visualization, while neuroendoscopy ensures minimally invasive access and reduced tissue trauma. Integrating these methods optimizes treatment efficacy and clinical outcomes.
To evaluate the impact of combined microscopic and neuroendoscopic techniques on psychological, cognitive outcomes, and quality of life in patients with ruptured intracranial aneurysms.
The study focused on 189 patients with intracranial aneurysm rupture and hemorrhage from January 2020 to May 2024 as the objects of observation and analysis. They were randomly divided into a control group (treated with simple microscope surgery, = 94) and an observation group (treated with microscope combined with neuroendoscopy, = 95). The treatment effects of the two groups were observed, mainly including depression and anxiety scale scores, cognitive function assessment results and quality of life assessment data.
Before treatment, the depression and anxiety scale scores, cognitive function assessment results and quality of life assessment data of the two groups of patients at different time points were compared, and there was no statistically significant difference ( > 0.05). After microscope combined with neuroendoscopy treatment, the study revealed that the observation group surpassed the control group in alleviating depression and anxiety, accelerating cognitive function recovery, and enhancing quality of life, with these differences being statistically significant ( < 0.05).
Surgical treatment combined with microscopy and neuroendoscopy has a significant positive effect on the mental health, cognitive function and overall quality of life of patients with intracranial aneurysm rupture and bleeding, can shorten the operation time and treatment time, and provides a new strategic reference for clinical treatment.
颅内动脉瘤以动脉壁局灶性扩张为特征，因其有破裂和出血的风险，给神经外科手术带来了重大挑战，可导致严重的临床后果，包括死亡。患者常经历深刻的心理和社会影响，如抑郁、焦虑和认知障碍，影响其生活质量。快速进展和高死亡率需要及时干预。神经外科技术的进步，包括显微手术和神经内镜，具有明显优势。显微手术提供精确性和直接可视化，而神经内镜确保微创入路并减少组织创伤。整合这些方法可优化治疗效果和临床结局。
评估显微手术与神经内镜联合技术对破裂颅内动脉瘤患者心理、认知结局及生活质量的影响。
本研究以2020年1月至2024年5月的189例颅内动脉瘤破裂出血患者为观察分析对象。将他们随机分为对照组（单纯显微手术治疗，n = 94）和观察组（显微手术联合神经内镜治疗，n = 95）。观察两组的治疗效果，主要包括抑郁和焦虑量表评分、认知功能评估结果及生活质量评估数据。
治疗前，比较两组患者在不同时间点的抑郁和焦虑量表评分、认知功能评估结果及生活质量评估数据，差异无统计学意义（P > 0.05）。显微手术联合神经内镜治疗后，研究发现观察组在缓解抑郁和焦虑、加速认知功能恢复及提高生活质量方面优于对照组，差异有统计学意义（P < 0.05）。
显微手术与神经内镜联合的手术治疗对颅内动脉瘤破裂出血患者的心理健康、认知功能及总体生活质量有显著积极影响，可缩短手术时间和治疗时间，为临床治疗提供了新的策略参考。
