Gräs Søren, Starck Marianne, Jangö Hanna, Lose Gunnar, Klarskov Niels
Department of Obstetrics and Gynecology, Herlev Gentofte University Hospital, Herlev, Denmark.
Pelvic Floor Center, Department of Surgery, Skåne University Hospital, Malmö, Sweden.
Int Urogynecol J. 2025 Mar 25. doi: 10.1007/s00192-025-06110-4.
Women undergoing a vacuum-assisted (VA) delivery are at an increased risk of experiencing an obstetric anal sphincter injury (OASI). Studies using three-dimensional-endoanal ultrasound (3D-EAUS) have shown that not all OASIs are recognized immediately postpartum. In primipara with VA deliveries, the presence of and the potential clinical implications of undetected OASIs are undetermined and consequently, we examined prospectively a 1-year cohort of this population. We hypothesized that the total rate of OASIs would be higher than the clinically reported rates and wanted to identify potential associated predictors.
The participants were examined 10-14 days postpartum with 3D-EAUS. Two experienced examiners, blinded to the clinical data, rated the results. The primary outcome was the combined rate of clinically recognized OASIs and clinically unrecognized ultrasound anal sphincter injuries. Logistic regression analysis was used to calculate the odds ratios for selected variables.
Of 334 eligible women, 271 (81%) were included. The total rate of OASIs was 19% (95% CI 14-24; 14% clinically recognized and 5% clinically unrecognized). Prolonged second-stage/maternal exhaustion, occiput posterior presentation, and birthweight ≥ 4000g were significant and independent risk factors, increasing the odds two- to three-fold. The indication fetal distress alone or in combination with others significantly reduced the odds.
About 1 in 5 primipara undergoing a VA delivery experienced an OASI and about one quarter of them were not recognized clinically. The VA procedure is a modifiable intervention, and the identified risk and protective factors may help clinicians to decide whether it should be performed.
接受真空辅助(VA)分娩的女性发生产科肛门括约肌损伤(OASI)的风险增加。使用三维肛管超声(3D-EAUS)的研究表明,并非所有OASI在产后立即被识别。在初产妇VA分娩中,未检测到的OASI的存在及其潜在临床意义尚未确定,因此,我们对该人群进行了为期1年的前瞻性队列研究。我们假设OASI的总发生率高于临床报告的发生率,并希望确定潜在的相关预测因素。
在产后10 - 14天对参与者进行3D-EAUS检查。两名经验丰富的检查人员在不知道临床数据的情况下对结果进行评分。主要结局是临床认可的OASI和临床未认可的超声肛门括约肌损伤的综合发生率。采用逻辑回归分析计算选定变量的比值比。
在334名符合条件的女性中,271名(81%)被纳入研究。OASI的总发生率为19%(95%CI 14 - 24;14%为临床认可,5%为临床未认可)。第二产程延长/产妇衰竭、枕后位和出生体重≥4000g是显著且独立的危险因素,使几率增加两到三倍。单纯或与其他因素联合出现的胎儿窘迫指征显著降低了几率。
约五分之一接受VA分娩的初产妇发生了OASI,其中约四分之一在临床上未被识别。VA手术是一种可改变的干预措施,确定的风险和保护因素可能有助于临床医生决定是否应进行该手术。