Vaziri Nima, Dehghannoudeh Gholamreza, Sharififar Fariba, Dabaghzadeh Fatemeh, Sarafzadeh Farhad, Ahmadi Bizhan
Herbal and Traditional Medicines Research Center, Kerman University of Medical Sciences, Kerman 761, Iran.
Pharmaceutics Research Center, Institute of Neuropharmacology, Kerman University of Medical Sciences, Kerman 761, Iran.
J Tradit Chin Med. 2025 Apr;45(2):437-442. doi: 10.19852/j.cnki.jtcm.2025.02.009.
OBJECTIVE: To evaluate the effect of this plant as adjunctive therapy on () eradication. METHODS: The plant capsules were prepared and their physicochemical properties were assessed. In this clinical trial, 99 patients with infection were randomized to receive Rech. f. & Esfand () or placebo capsules for two weeks. All the patients in both groups received clarithromycin-based triple therapy. Both intention to treat and per protocol analyses were performed. Eradication rates, treatment side effects, and medication compliance were evaluated in both groups. RESULTS: H. pylori eradication rate of all the randomized participants was 59.59%. The eradication rate of was significantly higher in group compared with that in the placebo group for per protocol analysis (84.62%, = 0.026) but not for intention to treat one (65.31%, 0.252). There were no significant differences between the two groups regarding the frequencies of the medications side effects and the patients with poor compliance. CONCLUSION: The use of as adjunctive therapy to 14-day clarithromycin-based triple therapy might improve eradication rate.
J Tradit Chin Med. 2025-4
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