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马尾综合征预后及手术治疗中脱垂与管腔比率(PCR)的影响。

The impact of prolapse to canal ratio (PCR) in cauda equina syndrome outcomes and operative management.

作者信息

Baig Mirza Asfand, Fayez Feras, Rashed Sami, Shahid Ammal Bibi, Sharma Chaitanya, Suvarna Rishabh, Vastani Amisha, Serag Ahmed, Nader-Sepahi Ali, Montgomery Alexander, Malik Irfan, Grahovac Gordan, Arvin Babak, Sadek Ahmed-Ramadan

机构信息

Department of Neurosurgery, Queens Hospital, Romford, London, UK.

Charing Cross Hospital, London, UK.

出版信息

Eur Spine J. 2025 Apr 2. doi: 10.1007/s00586-025-08816-x.

Abstract

PURPOSE

This study aimed to evaluate the prolapse to canal ratio (PCR) and its long-term impact on outcomes in cauda equina syndrome (CES).

METHODS

A 5-year retrospective cohort study was conducted across two neurosurgical centers, including adult patients diagnosed with CES due to herniated lumbar discs, treated with laminectomy and/or discectomy, with available radiological data and follow-up. PCR was calculated as the proportion of the disc prolapse cross-sectional area to the total spinal canal area. MRI scans were independently analyzed by two investigators, with random verification by a third. Patient demographics, symptoms, treatment, and follow-up data were also collected.

RESULTS

Among 137 patients, cohorts were divided using a PCR cut-off of 0.5. Patients with PCR > 0.5 were significantly more likely to have persistent symptoms at follow-up (OR 3.93, CI 2.25-7.34, p < 0.0001). This risk increased with higher PCR thresholds (> 0.75 and > 0.8). PCR > 0.5 also predicted a greater likelihood of requiring a full laminectomy over minimally invasive approaches (OR 2.14, 95% CI 1.3-3.6, p < 0.005). Lower PCR (< 0.5) was associated with reduced complication rates and shorter hospital stays.

CONCLUSIONS

PCR is a valuable predictor of persistent pain and functional deficits following CES surgery and could be used to guide patient counseling before surgical intervention.

摘要

目的

本研究旨在评估马尾综合征(CES)中脱垂与椎管比率(PCR)及其对预后的长期影响。

方法

在两个神经外科中心进行了一项为期5年的回顾性队列研究,纳入因腰椎间盘突出症诊断为CES的成年患者,接受椎板切除术和/或椎间盘切除术治疗,有可用的放射学数据和随访资料。PCR计算为椎间盘脱垂横截面积与整个椎管面积的比例。MRI扫描由两名研究者独立分析,第三名研究者进行随机核查。还收集了患者的人口统计学资料、症状、治疗及随访数据。

结果

137例患者中,采用PCR临界值0.5进行分组。PCR>0.5的患者在随访时出现持续性症状的可能性显著更高(比值比3.93,可信区间2.25 - 7.34,p<0.0001)。随着PCR阈值升高(>0.75和>0.8),这种风险增加。PCR>0.5还预示相比于微创方法更有可能需要进行全椎板切除术(比值比2.14,95%可信区间1.3 - 3.6,p<0.005)。较低的PCR(<0.5)与较低的并发症发生率和较短的住院时间相关。

结论

PCR是CES手术后持续性疼痛和功能障碍的有价值预测指标,可用于在手术干预前指导患者咨询。

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