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[淋巴血管系统成像技术]

[Imaging of the lymphatic vascular system-techniques].

作者信息

Henkel A, Pieper Claus C

机构信息

Sektion für minimal invasive Lymphgefäßtherapie, Klinik für Diagnostische und Interventionelle Radiologie, Universitätsklinikum Bonn, Venusberg-Campus 1, 53127, Bonn, Deutschland.

出版信息

Radiologie (Heidelb). 2025 May;65(5):307-315. doi: 10.1007/s00117-025-01440-2. Epub 2025 Apr 4.

Abstract

CLINICAL/METHODICAL ISSUE: Imaging of the lymphatic vascular system is comparatively difficult and logistically demanding.

STANDARD RADIOLOGICAL METHODS

The field has developed significantly in recent decades. The longest established techniques are conventional X‑ray lymphangiography and lymphoscintigraphy.

METHODOLOGICAL INNOVATIONS

In recent years, magnetic resonance (MR) and computed tomography (CT) lymphangiography have been developed using different contrast medium (CM) techniques. For interstitial lymphangiography, CM is injected intracutaneously, and absorbed and drained by the lymphatic system. For direct techniques, CM is injected directly into a lymph node or a prepared lymph vessel.

PERFORMANCE

Lymphangiography procedures offer high anatomical and/or temporal resolution that have method-related differences. They allow better morphological assessment of the lymph vessels compared to lymphoscintigraphy. Furthermore, MR and CT lymphangiography are less invasive than conventional x‑ray lymphangiography.

EVALUATION

MR lymphangiography in particular allows dynamic assessment of lymph flow through repetitive imaging, which is particularly valuable in complex situations. While MR lymphangiography is now established in centers despite the off-label use of CM, data regarding CT lymphangiography is still very limited.

PRACTICAL RECOMMENDATIONS

A number of specific lymphatic imaging techniques are available at specialized centers.

摘要

临床/方法学问题:淋巴血管系统的成像相对困难,且对后勤保障要求较高。

标准放射学方法

近几十年来该领域有了显著发展。最古老的技术是传统的X线淋巴管造影术和淋巴闪烁造影术。

方法学创新

近年来,利用不同的造影剂(CM)技术开发了磁共振(MR)和计算机断层扫描(CT)淋巴管造影术。对于间质淋巴管造影,造影剂经皮注射,由淋巴系统吸收和引流。对于直接技术,造影剂直接注入淋巴结或准备好的淋巴管。

性能

淋巴管造影程序提供了具有方法相关差异的高解剖和/或时间分辨率。与淋巴闪烁造影术相比,它们能更好地对淋巴管进行形态学评估。此外,MR和CT淋巴管造影术比传统的X线淋巴管造影术侵入性更小。

评估

特别是MR淋巴管造影术允许通过重复成像对淋巴流动进行动态评估,这在复杂情况下尤为有价值。尽管造影剂属于超适应证使用,但MR淋巴管造影术目前已在各中心得到应用,而关于CT淋巴管造影术的数据仍然非常有限。

实际建议

在专业中心可采用多种特定的淋巴成像技术。

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