Zhao Ying, Qiao Yumiao, Hong Kai, Zhang Chao
Department of Medical Ultrasound, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, 1095 Jiefang Rd, Wuhan, 430030, China.
Eur J Med Res. 2025 Apr 7;30(1):254. doi: 10.1186/s40001-025-02530-6.
To clarify the difference between the alpha angles measured by European method and by AIUM method.
In this prospective study, infants less than 6-month-old with clinical suspicion of DDH were enrolled from the pediatric outpatient service in a large provincial teaching hospital from October 2022 to October 2023. The hips were examined according to the protocols described by AIUM guideline and by European consensus. The acetabular alpha angle was measured on the standard sections. Statistically significant difference between groups was determined by using a paired-sample t test.
A total of 225 infants (median age, 4.0 months [interquartile range, 3.3-5.2 months]; 104 boys) were enrolled into the study. The mean value of alpha angle measured by AIUM method (62.1°; 95% CI 61.7, 62.4) was smaller than that by European method (63.4°; 95% CI 63.1, 63.7) (P < 0.0001). The 95% limits of agreement between alpha angles measured by the two methods were - 6.6 to 9.2 degree. Alpha angle measured by AIUM method could diagnose DDH with low sensitivity (56% [9 of 16 hips; 95% CI 31, 79]) and specificity (78% [300 of 384 hips; 95% CI 74, 82]) with Graf's technique as a reference standard. The position of transducer arranged on the skin of infant by AIUM method was 1.6 ± 0.3 cm back to the position by European method.
Alpha angle measured by AIUM method is smaller than that by European method and should not be applied to Graf typing of DDH.
阐明欧洲方法和美国超声医学学会(AIUM)方法所测量的α角之间的差异。
在这项前瞻性研究中,2022年10月至2023年10月期间,从一所大型省级教学医院的儿科门诊招募了临床怀疑患有发育性髋关节发育不良(DDH)的6个月以下婴儿。按照AIUM指南和欧洲共识所描述的方案对髋关节进行检查。在标准切片上测量髋臼α角。采用配对样本t检验确定组间的统计学显著差异。
共有225名婴儿(中位年龄4.0个月[四分位间距3.3 - 5.2个月];104名男孩)纳入研究。AIUM方法测量的α角平均值(62.1°;95%可信区间61.7, 62.4)小于欧洲方法测量的平均值(63.4°;95%可信区间63.1, 63.7)(P < 0.0001)。两种方法测量的α角之间的95%一致性界限为 - 6.6至9.2度。以Graf技术作为参考标准,AIUM方法测量的α角诊断DDH的敏感性较低(56%[16个髋关节中的9个;95%可信区间31, 79]),特异性为78%[384个髋关节中的300个;95%可信区间74, 82])。AIUM方法在婴儿皮肤上布置换能器的位置比欧洲方法的位置向后1.6±0.3厘米。
AIUM方法测量的α角小于欧洲方法测量的α角,不应应用于DDH的Graf分型。