Fischer P, Remijn B, Brunekreef B, van der Lende R, Schouten J, Quanjer P
Int J Epidemiol. 1985 Jun;14(2):221-6. doi: 10.1093/ije/14.2.221.
The association between nitrogen dioxide levels in homes and pulmonary function of 97 non-smoking adult women was investigated in a rural area in the Netherlands. The study population was a sub-sample of a longitudinal field study on chronic non-specific lung diseases which was started in 1965. Pulmonary function tests were performed at three-yearly intervals. NO2 was measured for one week in the winter in kitchen, living room and bedroom of each home. Cross-sectional analyses showed negative associations between NO2 exposure and several pulmonary function parameters as measured in the 1982 study. No significant association could be found between NO2 exposure and pulmonary function decline since the start of the study.
在荷兰的一个农村地区,对97名不吸烟成年女性家中二氧化氮水平与肺功能之间的关联进行了调查。研究人群是始于1965年的一项关于慢性非特异性肺部疾病的纵向实地研究的子样本。肺功能测试每三年进行一次。在冬季,对每个家庭的厨房、客厅和卧室进行为期一周的二氧化氮测量。横断面分析显示,在1982年的研究中,二氧化氮暴露与多个肺功能参数之间存在负相关。自研究开始以来,未发现二氧化氮暴露与肺功能下降之间存在显著关联。