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微量营养素与牙周组织:一篇叙述性综述

Micronutrients and the Periodontium: A Narrative Review.

作者信息

Doshi Dhruvi, Kumar Santosh, Patel Bhavin, Chaudhari Dipak, Patel Shirishkumar, Hirani Tanvi, Patadiya Hiren H, Bhingradia Isha R, Haque Mainul

机构信息

Periodontology and Implantology, Karnavati School of Dentistry, Karnavati University, Gandhinagar, IND.

General Dentistry, My Dental Southbridge PLLC, Southbridge, USA.

出版信息

Cureus. 2025 Apr 4;17(4):e81694. doi: 10.7759/cureus.81694. eCollection 2025 Apr.


DOI:10.7759/cureus.81694
PMID:40190829
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11970441/
Abstract

This is a comprehensive narrative assessment of micronutrient relevance for periodontal health. The periodontium is a crucial and intricate structure that supports the tooth within the alveolar bone. Composed of four tissues with distinct embryological origins- the alveolar bone, cementum, gingiva, and periodontal ligament - the periodontium plays a fundamental role in maintaining dento-alveolar function and homeostasis. Periodontitis is gaining attention due to its widespread occurrence worldwide. This inflammatory condition disrupts the balance between the host immune response and microbial virulence factors. Connective tissue production and host defenses require proteins for periodontal health. Vegetable proteins support periodontal health by promoting tissue repair and immune function, while excessive dietary fats can exacerbate inflammation and increase the risk of periodontal disease (PD). Inflammation is further compounded due to dietary animal fats, which contribute to the risk of PD. Omega-3 fatty acids are well-known for their anti-inflammatory effects, which help reduce periodontal inflammation. Adequate intake of essential minerals and vitamins is required for maintaining periodontal health. Vitamins K, D, and A are crucial in maintaining oral epithelial integrity, facilitating bone development, and supporting overall tissue maintenance. Inadequate calcium (Ca²⁺) and magnesium (Mg²⁺) levels have been associated with severe PD. Antioxidants such as vitamin C help alleviate inflammation in periodontal tissues. As recognized by dental professionals, nutritional status plays a considerable role in an individual's risk of developing PD.

摘要

这是一篇关于微量营养素与牙周健康相关性的综合叙述性评估。牙周组织是一种关键且复杂的结构,它在牙槽骨内支撑着牙齿。牙周组织由四种具有不同胚胎学起源的组织组成——牙槽骨、牙骨质、牙龈和牙周韧带——在维持牙-牙槽功能和体内平衡方面发挥着重要作用。牙周炎因其在全球范围内的广泛发生而受到关注。这种炎症状态破坏了宿主免疫反应和微生物毒力因子之间的平衡。结缔组织生成和宿主防御需要蛋白质来维持牙周健康。植物蛋白通过促进组织修复和免疫功能来支持牙周健康,而过量的膳食脂肪会加剧炎症并增加患牙周病(PD)的风险。膳食中的动物脂肪会进一步加重炎症,增加患牙周病的风险。ω-3脂肪酸以其抗炎作用而闻名,有助于减轻牙周炎症。维持牙周健康需要充足摄入必需的矿物质和维生素。维生素K、D和A在维持口腔上皮完整性、促进骨骼发育和支持整体组织维持方面至关重要。钙(Ca²⁺)和镁(Mg²⁺)水平不足与严重的牙周病有关。维生素C等抗氧化剂有助于减轻牙周组织的炎症。正如牙科专业人员所认识到的,营养状况在个体患牙周病的风险中起着相当大的作用。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/60c1/11970441/e755842add65/cureus-0017-00000081694-i06.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/60c1/11970441/697377c7a835/cureus-0017-00000081694-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/60c1/11970441/72a238323e6c/cureus-0017-00000081694-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/60c1/11970441/e9c30f671ceb/cureus-0017-00000081694-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/60c1/11970441/dae826b9cce5/cureus-0017-00000081694-i04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/60c1/11970441/e32dfe66d7ba/cureus-0017-00000081694-i05.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/60c1/11970441/e755842add65/cureus-0017-00000081694-i06.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/60c1/11970441/697377c7a835/cureus-0017-00000081694-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/60c1/11970441/72a238323e6c/cureus-0017-00000081694-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/60c1/11970441/e9c30f671ceb/cureus-0017-00000081694-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/60c1/11970441/dae826b9cce5/cureus-0017-00000081694-i04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/60c1/11970441/e32dfe66d7ba/cureus-0017-00000081694-i05.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/60c1/11970441/e755842add65/cureus-0017-00000081694-i06.jpg

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Micronutrients and the Periodontium: A Narrative Review.

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本文引用的文献

[1]
The 6M Classification of Nutrients.

J Pak Med Assoc. 2025-3

[2]
Therapeutic Impact of Ascorbic Acid on Oral and Periodontal Tissues: A Systematic Literature Review.

Medicina (Kaunas). 2024-12-11

[3]
The Impact of Nutritional Components on Periodontal Health: A Literature Review.

Nutrients. 2024-11-15

[4]
Associations between single and multiple dietary vitamins and the risk of periodontitis: results from NHANES 2009-2014.

Front Nutr. 2024-4-8

[5]
Role of zinc in health and disease.

Clin Exp Med. 2024-2-17

[6]
Vitamin intake and periodontal disease: a meta-analysis of observational studies.

BMC Oral Health. 2024-1-20

[7]
Estimation of Vitamin D Levels Using a Chairside Diagnostic Test Kit in Patients with Gingivitis and Periodontitis: A Cross-Sectional Study.

J Int Soc Prev Community Dent. 2023-10-30

[8]
Vitamin D and Periodontal Health: A Systematic Review.

Cureus. 2023-10-26

[9]
Can vitamins improve periodontal wound healing/regeneration?

Periodontol 2000. 2024-2

[10]
Serum levels of various vitamins in periodontal health and disease- a cross sectional study.

J Oral Biol Craniofac Res. 2023

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