一名甲状腺功能正常的13岁女孩的弥漫性硬化型乳头状甲状腺癌：一种罕见的甲状腺恶性肿瘤

Diffuse Sclerosing Variant of Papillary Thyroid Carcinoma in an Euthyroid 13-year-old Girl: A Rare Thyroid Malignancy.

作者信息

Prasad Pallavi, Jain Shweta, Chand Gyan

机构信息

Department of Pathology, SGPGIMS, Lucknow, Uttar Pradesh, India.

Department of Endocrine Surgery, SGPGIMS, Lucknow, Uttar Pradesh, India.

出版信息

J Indian Assoc Pediatr Surg. 2025 Mar-Apr;30(2):238-240. doi: 10.4103/jiaps.jiaps_210_24. Epub 2025 Jan 2.

DOI:10.4103/jiaps.jiaps_210_24

PMID:40191475

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11968041/

Abstract

Diffuse sclerosing variant is an uncommon subtype of papillary thyroid carcinoma (PTC). The clinical presentation often resembles Hashimoto's thyroiditis. Histopathological features are similar to conventional PTC; however, diffuse involvement of both lobes, extensive cervical lymphadenopathy, numerous psammoma bodies, extensive lymphocytic infiltrates, and fibrosis suggest a high possibility of this rare variant.

摘要

弥漫性硬化型是乳头状甲状腺癌（PTC）的一种罕见亚型。其临床表现常类似于桥本甲状腺炎。组织病理学特征与传统PTC相似；然而，双侧叶弥漫性受累、广泛的颈部淋巴结肿大、大量砂粒体、广泛的淋巴细胞浸润和纤维化提示这种罕见亚型的可能性很大。