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犬肠道淋巴管扩张症:临床、超声、内镜及应变弹性成像方面

Intestinal lymphangiectasia in a dog: Clinical, ultrasonographic, endoscopic, and strain elastographic aspects.

作者信息

Oliveira Iago Martins, da Silva Wanessa Patrícia Rodrigues, Mariana Moreira Lopes, Cristina Borges Naida

机构信息

Programa de Pós-graduação em Ciência Animal, Escola de Veterinária e Zootecnia, Universidade Federal de Goiás, Goiânia, Brazil.

Escola de Ciências Médicas e da Vida, Pontifícia Universidade Católica de Goiás, Goiânia, Brazil.

出版信息

Open Vet J. 2025 Feb;15(2):1056-1063. doi: 10.5455/OVJ.2025.v15.i2.54. Epub 2025 Feb 28.

Abstract

BACKGROUND

Primary intestinal lymphangiectasia in dogs is a condition characterized by dilation of the lymphatic vessels in the intestine. It has serious consequences, such as protein loss. Early diagnosis and appropriate treatment are essential for the quality of life of affected animals.

CASE DESCRIPTION

A 10-month-old female Border collie with persistent diarrhea for 3 months associated with weight loss, emesis, steatorrhea, and anorexia. During the investigation, the patient showed signs of dehydration; based on inspection and bone and muscle palpation, there was a reduction in the body condition score, as well as limb edema. An abdominal ultrasound revealed intestinal wall thickening and signs indicative of lymphangiectasia. The strain elastography revealed changes in intestinal rigidity parameters. After upper digestive endoscopy and histopathological examination, the female patient was diagnosed with intestinal lymphangiectasia. The female patient was treated with a low-fat diet and immunosuppressive drugs, which resulted in clinical and laboratory improvement and a reduction in the hardness rate on elastography.

CONCLUSION

This case highlights the clinical, ultrasonographic, endoscopic, and strain elastographic findings of intestinal lymphangiectasia in a dog, demonstrating elastography's potential as a diagnostic and monitoring tool while confirming the disease's responsiveness to immunosuppressive therapy and dietary management.

摘要

背景

犬原发性肠淋巴管扩张症是一种以肠淋巴管扩张为特征的疾病。它会导致诸如蛋白质流失等严重后果。早期诊断和适当治疗对于患病动物的生活质量至关重要。

病例描述

一只10个月大的雌性边境牧羊犬持续腹泻3个月,伴有体重减轻、呕吐、脂肪泻和厌食。在检查过程中,患者出现脱水迹象;通过检查以及骨骼和肌肉触诊发现,身体状况评分降低,同时伴有肢体水肿。腹部超声显示肠壁增厚以及淋巴管扩张的迹象。应变弹性成像显示肠道硬度参数发生变化。经过上消化道内镜检查和组织病理学检查,该雌性患者被诊断为肠淋巴管扩张症。该雌性患者接受了低脂饮食和免疫抑制药物治疗,临床和实验室检查结果均有改善,弹性成像硬度率降低。

结论

本病例突出了犬肠淋巴管扩张症的临床、超声、内镜及应变弹性成像表现,证明了弹性成像作为诊断和监测工具的潜力,同时证实了该疾病对免疫抑制治疗和饮食管理的反应。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/27ca/11974309/b2a23a80f4ed/OpenVetJ-15-1056-g001.jpg

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