Bautista-González Elysse, Muñoz Rocha Teresa Verenice, Soto-Perez-de-Celis Enrique, Vindrola-Padros Cecilia, Peasey Anne, Pikhart Hynek
Institute of Epidemiology and Health Care, Research Department of Epidemiology and Public Health, University College London, London, WC1E 7HB, United Kingdom.
Center for Research in Nutrition and Health, National Institute of Public Health, Cuernavaca, Morelos, 62100, Mexico.
Oncologist. 2025 Apr 4;30(4). doi: 10.1093/oncolo/oyae358.
Lung cancer management involves navigating a complex pathway from symptom onset to treatment initiation, where delays can compromise outcomes.
To identify the length of treatment intervals among Mexican lung cancer patients, compare treatment intervals to results from other countries, and identify determinants of delays.
Retrospective study collecting patient records and exploring the treatment interval in lung cancer.
The study was conducted at Mexico's National Cancer Institute.
2645 lung cancer patients with a confirmed diagnosis between 2004 and 2021 were included in the analysis.
Social determinants of health.
Treatment interval (from diagnosis to treatment).
Logistic regression models revealed significant associations between delays and various factors, including marital status, education, region, first symptom at presentation, treatment type, and political period. A comparison with international guidelines highlighted substantial delays in patients diagnosed at the Instituto Nacional de Cancerología and diagnosed externally.
Targeted interventions should consider patient characteristics to enhance care efficiency. Concerns should be raised about the observed increase in treatment intervals from 2014 and the associated impact on survival rates. There is an urgency for timely interventions, continuous research, and collaborative efforts to optimize care delivery and outcomes for lung cancer patients in Mexico.
肺癌管理涉及从症状出现到开始治疗的复杂过程，延误可能会影响治疗结果。
确定墨西哥肺癌患者的治疗间隔时长，将治疗间隔与其他国家的结果进行比较，并确定延误的决定因素。
回顾性研究，收集患者记录并探索肺癌的治疗间隔。
该研究在墨西哥国家癌症研究所进行。
分析纳入了2004年至2021年间确诊的2645例肺癌患者。
健康的社会决定因素。
治疗间隔（从诊断到治疗）。
逻辑回归模型显示延误与多种因素之间存在显著关联，包括婚姻状况、教育程度、地区、就诊时的首发症状、治疗类型和政治时期。与国际指南的比较突出了在国家癌症研究所确诊的患者和外部确诊的患者存在的显著延误。
有针对性的干预措施应考虑患者特征，以提高护理效率。应关注2014年以来观察到的治疗间隔增加以及对生存率的相关影响。迫切需要及时进行干预、持续研究并共同努力，以优化墨西哥肺癌患者的护理提供和治疗结果。
