Mayo Clinic Ambulance Service is testing a novel combination of technologies to enhance the ability to provide prehospital telemedicine connecting physicians with paramedics. Mayo Clinic Ambulance Service partnered with start-up company OPTAC-X to field test a novel head-mounted video camera connected with a satellite communications terminal to bring medical control emergency medicine physicians to the patient and paramedic by video. The authors believe this is the first report of a physician providing medical guidance to paramedics resuscitating an out-of-hospital cardiac arrest using these technologies.