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多机构微创阑尾补片输尿管成形术治疗小儿复杂性近端输尿管狭窄的长期疗效

Long-term Outcomes of Multi-institutional Minimally Invasive Appendiceal Onlay Ureteroplasty for Managing Complex Proximal Ureteral Strictures in Pediatric Patients.

作者信息

Cao Hualin, Wu Yangyang, Li Pin, Yi Xiaoyu, Zhang Xiaowei, Jia Hongshuai, Jin Ruyue, Deng Xiangling, Tao Tian, Ma Lifei, Zhou Xiaoguang, An Nini, Yang Yanfang, Bi Jianpeng, Zhang Qian, Li Ji, Zhou Yun, Qi Can, Zhao Jiawen, Liu Bowen, Liao Songbai, Tao Yuandong, Cheng Jiwen, Zhou Huixia

机构信息

Department of Urology, Nanxishan Hospital (the Second People's Hospital) of Guangxi Zhuang Autonomous Region, Guilin, China.

Department of Urology, Senior Department of Pediatrics, The Seventh Medical Center of Chinese PLA General Hospital, Beijing, China.

出版信息

J Pediatr Surg. 2025 Jul;60(7):162316. doi: 10.1016/j.jpedsurg.2025.162316. Epub 2025 Apr 8.

Abstract

PURPOSE

We report the long-term outcomes of laparoscopic and robotic-assisted appendiceal onlay ureteroplasty (AOU) for complex proximal ureteral (CPU) strictures in children across multiple institutions.

METHODS

Retrospective review of patients who underwent laparoscopic or robotic AOU for CPU between 2010 and 2020. Patient characteristics, perioperative surgical data, and follow-up data are described. The surgical approach was adjusted to the stricture length and location, involving a ventral incision or excision of the diseased ureter followed by repair with an onlay appendiceal flap. Success was established by the presence of symptomatic relief and the absence of obstruction on imaging assessments.

RESULTS

Twenty-nine patients underwent minimally invasive AOU of CPU (12 laparoscopy, 17 robot-assisted). The median age at surgery was 48 months (IQR, 36.5-69.0). The median stricture length measured 4.0 cm (IQR, 3.3-5.0), operative time was 162.0 min (IQR, 137.0-178.0), and estimated blood loss was 25.0 ml (IQR, 20.0-30.0). No open conversions and intraoperative complications occurred. Ventral-side onlay ureteroplasty was performed in 14 (48.3 %) patients (including two onlay augmented pyeloplasty) and Dorsal-side reconstruction ureteroplasty was performed in 15 (51.7 %) patients. Overall, 18 patients had grade Ⅰ or Ⅱ Clavien-Dindo postoperative complications and one patient developed a grade Ⅲ complication. Surgical success was achieved in 28/29 (96.6 %) patients at a median follow-up of 6.0 years (IQR, 5.0-7.5).

CONCLUSION

Minimally invasive AOU is a safe, feasible, and effective technique for managing CPU strictures in children with good long-term outcomes.

摘要

目的

我们报告了多个机构中采用腹腔镜和机器人辅助阑尾覆盖输尿管成形术(AOU)治疗儿童复杂性近端输尿管(CPU)狭窄的长期疗效。

方法

对2010年至2020年间接受腹腔镜或机器人辅助AOU治疗CPU的患者进行回顾性研究。描述了患者特征、围手术期手术数据和随访数据。手术方式根据狭窄长度和位置进行调整,包括腹部切口或切除病变输尿管,然后用阑尾覆盖瓣进行修复。通过症状缓解和影像学评估无梗阻来确定手术成功。

结果

29例患者接受了CPU的微创AOU(12例腹腔镜手术,17例机器人辅助手术)。手术时的中位年龄为48个月(四分位间距,36.5 - 69.0)。中位狭窄长度为4.0 cm(四分位间距,3.3 - 5.0),手术时间为162.0分钟(四分位间距,137.0 - 178.0),估计失血量为25.0 ml(四分位间距,20.0 - 30.0)。未发生开放手术转换和术中并发症。14例(48.3%)患者进行了腹侧覆盖输尿管成形术(包括2例覆盖增强肾盂成形术),15例(51.7%)患者进行了背侧重建输尿管成形术。总体而言,18例患者出现Ⅰ级或Ⅱ级Clavien-Dindo术后并发症,1例患者出现Ⅲ级并发症。28/29(96.6%)例患者手术成功,中位随访时间为6.0年(四分位间距,5.0 - 7.5)。

结论

微创AOU是治疗儿童CPU狭窄的一种安全、可行且有效的技术,长期疗效良好。

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