Speicher Tilman, Bastian Moritz B, Christofyllakis Konstantinos, Rosar Florian, Ezziddin Samer, Burgard Caroline
Department of Nuclear Medicine, Saarland University, 66421 Homburg, Germany.
Department of Hematologic Oncology, Saarland University, 66421 Homburg, Germany.
Diagnostics (Basel). 2025 Mar 28;15(7):862. doi: 10.3390/diagnostics15070862.
We present an F-fluorodeoxyglucose ([F]FDG) positron emission tomography/computed tomography (PET/CT) scan of a 27 y/o patient with long-standing significant B symptoms, diffuse bone pain, increased inflammation parameters, and polydipsia revealing multiple FDG-avid osteolytic lesions of the axial skeleton including a vertebra plana of T7 and paraosseous soft tissue lesions. A CT-guided biopsy confirmed the diagnosis of Langerhans cell histiocytosis (LCH). This case highlights the importance of considering LCH in young patients with vertebral collapse and underscores the role of PET/CT imaging in establishing an accurate diagnosis.
我们展示了一名27岁患者的氟脱氧葡萄糖（[F]FDG）正电子发射断层扫描/计算机断层扫描（PET/CT）图像，该患者长期存在明显的B症状、弥漫性骨痛、炎症指标升高及烦渴，检查发现其轴向骨骼有多个FDG摄取增加的溶骨性病变，包括T7椎体扁平及骨旁软组织病变。CT引导下活检确诊为朗格汉斯细胞组织细胞增多症（LCH）。该病例突出了在年轻椎体塌陷患者中考虑LCH的重要性，并强调了PET/CT成像在准确诊断中的作用。
