Turker Kader Izim, Yuzbasioglu Emir, Smail Ferruh Semir, Ilhan Ceylan
Assistant Professor, Department of Prosthodontics, School of Dental Medicine, Bahcesehir University, Istanbul, Turkey.
Professor, Private Practice, Istanbul, Turkey.
J Prosthet Dent. 2025 Jun;133(6):1584.e1-1584.e8. doi: 10.1016/j.prosdent.2025.03.036. Epub 2025 Apr 10.
The color stability of computer-aided design and computer-aided manufacture (CAD-CAM) resin-based materials can be affected by their composition and exposure to different mouth rinses. However, the impact of different mouth rinse formulations on these materials remains unclear.
The purpose of this in vitro study was to investigate the effect of different mouth rinses on the color stability of CAD-CAM resin-based materials over time.
A total of 180 specimens of 5 CAD-CAM resin-based materials were fabricated: a polymer-infiltrated ceramic network (PICN) (Vita Enamic; ENA), resin nanoceramics (GC Cerasmart; CERA, Brilliant Crios; BRC), a resin nanohybrid (Grandio; GRD), and a resin composite (KZR-CAD HR2; KZR). A lithium disilicate ceramic (IPS e.max CAD; EMX) served as the control (n=30). Specimens were immersed in alcohol-containing (Listerine Cool Mint; LIS), alcohol-free (Oral-B complete; ORLB), zinc-chloride containing (Pharmol Zn; PHR), hypochlorous acid-containing (Briotech Pure; BRT) mouth rinses, and artificial saliva (CON) for 12 hours (t0.5), 2.5 days (t2.5), and 5 days (t5) of simulated exposure equivalent to 1, 5, and 10 years. Color differences (ΔE00) were calculated at each time point. The effects of material, mouth rinse, and time were analyzed using 3-way robust ANOVA with Bonferroni post hoc tests (α=.05).
EMX exhibited the highest color stability, while the GRD showed the largest discoloration (P<.001). LIS and ORLB mouth rinses caused significantly higher ΔE00 values than other solutions (P<.001). Discoloration increased with longer exposure times (P=.001). Among all groups, BRC immersed in LIS exhibited the most pronounced color change, while EMX in CON showed the least (P=.001).
CAD-CAM resin-based materials undergo a larger color change than lithium disilicate ceramic, with variations depending on composition and mouth rinse type. While alcohol-containing mouth rinse (LIS) induced the highest discoloration, particularly in the resin nanoceramic (BRC), the highest discoloration after a simulated prolonged exposure of 10 years was observed in the resin nanohybrid (GRD). Notably, the alcohol-free ORLB also led to significant discoloration, suggesting that other ingredients beyond alcohol contribute to staining.
计算机辅助设计与计算机辅助制造（CAD-CAM）树脂基材料的颜色稳定性会受到其成分以及接触不同漱口水的影响。然而，不同漱口水配方对这些材料的影响仍不明确。
本体外研究的目的是调查不同漱口水随时间推移对CAD-CAM树脂基材料颜色稳定性的影响。
制作了5种CAD-CAM树脂基材料的总共180个样本：聚合物渗透陶瓷网络（PICN）（维他易美；ENA）、树脂纳米陶瓷（GC晶瓷；CERA、炫美克瑞斯；BRC）、树脂纳米混合材料（格莱迪欧；GRD）以及树脂复合材料（KZR-CAD HR2；KZR）。二硅酸锂陶瓷（义获嘉e.max CAD；EMX）作为对照（n = 30）。样本分别浸泡在含酒精（李施德林冰蓝薄荷味；LIS）、不含酒精（欧乐B全效；ORLB）、含氯化锌（法莫锌；PHR）、含次氯酸（百欧泰洁；BRT）的漱口水以及人工唾液（CON）中12小时（t0.5）、2.5天（t2.5）和5天（t5），模拟相当于1年、5年和10年的暴露时间。在每个时间点计算颜色差异（ΔE00）。使用三因素稳健方差分析及Bonferroni事后检验（α = 0.05）分析材料、漱口水和时间的影响。
EMX表现出最高的颜色稳定性，而GRD变色最大（P < 0.001）。LIS和ORLB漱口水导致的ΔE00值显著高于其他溶液（P < 0.001）。变色程度随暴露时间延长而增加（P = 0.001）。在所有组中，浸泡在LIS中的BRC颜色变化最明显，而浸泡在CON中的EMX颜色变化最小（P = 0.001）。
CAD-CAM树脂基材料比二硅酸锂陶瓷发生更大的颜色变化，其变化因成分和漱口水类型而异。含酒精漱口水（LIS）导致的变色最高，尤其是在树脂纳米陶瓷（BRC）中，而在模拟10年长期暴露后，树脂纳米混合材料（GRD）变色最高。值得注意的是，不含酒精的ORLB也导致显著变色，表明除酒精外的其他成分也会导致染色。
